Gene: AT4G05520

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G05520
  • Transcript Identifier AT4G05520.1
  • Gene Type Coding gene
  • Location Chr4 : 2804522-2807833 : positive

Gene Family Information

  • ID HOM05D001939
  • #Genes/#Species 340/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G05520.1
  • symbol EHD2
  • Alias ATEHD2,EPS15 homology domain 2
  • uniprot B3LF48

Descriptions

  • Description EPS15 homology domain 2
  • Computational description EPS15 homology domain 2 (EHD2); FUNCTIONS IN: GTP binding, GTPase activity, calcium ion binding; INVOLVED IN: endocytosis; LOCATED IN: plasma membrane, microsome, membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: EF-HAND 2 (InterPro:IPR018249), EPS15 homology (EH) (InterPro:IPR000261), Dynamin, GTPase domain (InterPro:IPR001401), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: EPS15 homology domain 1 (TAIR:AT3G20290.2); Has 2647 Blast hits to 1775 proteins in 263 species: Archae - 2; Bacteria - 75; Metazoa - 1675; Fungi - 405; Plants - 219; Viruses - 0; Other Eukaryotes - 271 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016197
IBA
Gene Ontologyendosomal transport1
GO:0006897
IEA
GOA Databaseendocytosis
GO:0006897
IMP
IBA
Gene Ontologyendocytosis1 2
GO:0032956
IMP
Gene Ontologyregulation of actin cytoskeleton organization3
GO:0051260
IDA
Gene Ontologyprotein homooligomerization2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005509
IEA
Gene Ontologycalcium ion binding
GO:0005509
IEA
InterProcalcium ion binding
GO:0005515
IPI
Gene Ontologyprotein binding2
GO:0005515
IEA
InterProprotein binding
GO:0005525
IEA
GOA DatabaseGTP binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0003924
IEA
GOA DatabaseGTPase activity
GO:0003925
IEA
Gene OntologyG protein activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IDA
Gene Ontologymembrane2
GO:0005768
IEA
GOA Databaseendosome
GO:0009506
IDA
GOA Databaseplasmodesma
GO:0009506
HDA
Gene Ontologyplasmodesma4
GO:0005634
IEA
GOA Databasenucleus
GO:0005886
IEA
GOA Databaseplasma membrane
GO:0005886
IDA
ISM, IBA
Gene Ontologyplasma membrane1 2
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
IDA
IBA
Gene Ontologycytoplasm1 2
GO:0010008
IEA
GOA Databaseendosome membrane
GO:0043231
IDA
IBA
Gene Ontologyintracellular membrane-bounded organelle1 2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR000261 EH domain
IPR031692 EH domain-containing protein, N-terminal
IPR040990 Domain of unknown function DUF5600
IPR045063 Dynamin, N-terminal
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR011992 EF-hand domain pair
IPR002048 EF-hand domain
Mapman id Description
22.4.4.1 Vesicle trafficking.endocytic trafficking.endocytic recycling.regulatory protein (EHD)