Gene: AT4G04860

General Information

Structural Information

Species Arabidopsis thaliana
Gene Identifier AT4G04860
Transcript Identifier AT4G04860.1
Gene Type Coding gene
Location Chr4 : 2460135-2461378 : positive

Gene Family Information

Homologous GF
Orthologous GF

ID HOM05D001731
#Genes/#Species 374/99
Phylogenetic origin

ID ORTHO05D004784
#Genes/#Species 171/99
Phylogenetic origin

Gene Duplication Information

Block Duplication Block duplicate

Labels

Identifiers

tid AT4G04860.1
symbol DER2.2
uniprot Q9ZS88

Descriptions

Description DERLIN-2.2

Computational description DERLIN-2.2 (DER2.2); CONTAINS InterPro DOMAIN/s: Der1-like (InterPro:IPR007599); BEST Arabidopsis thaliana protein match is: DERLIN-2.1 (TAIR:AT4G21810.1); Has 863 Blast hits to 862 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 343; Fungi - 190; Plants - 145; Viruses - 0; Other Eukaryotes - 185 (source: NCBI BLink).

Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0030968	IBA	Gene Ontology	endoplasmic reticulum unfolded protein response	1
GO:0030433	IBA	Gene Ontology	ubiquitin-dependent ERAD pathway	1

Molecular Function

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0051787	IBA	Gene Ontology	misfolded protein binding	1
GO:1990381	IBA	Gene Ontology	ubiquitin-specific protease binding	1

Cellular Component

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0000839	IBA	Gene Ontology	Hrd1p ubiquitin ligase ERAD-L complex	1
GO:0030176	IBA	Gene Ontology	integral component of endoplasmic reticulum membrane	1
GO:0005789	IEA	GOA Database	endoplasmic reticulum membrane
GO:0016021	IEA	GOA Database	integral component of membrane
GO:0016020	IEA	GOA Database	membrane
GO:0005783	IEA	GOA Database	endoplasmic reticulum

Color Legend

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR007599	Derlin
IPR035952	Rhomboid-like superfamily

Mapman id	Description
19.2.4.2.2.2	Protein homeostasis.ubiquitin-proteasome system.membrane-associated protein degradation.ER-associated protein degradation (ERAD).substrate extraction.membrane protein retrotranslocase (DFM1)