Gene: AT4G00570

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT4G00570
  • Transcript Identifier AT4G00570.1
  • Gene Type Coding gene
  • Location Chr4 : 242817-246522 : negative

Gene Family Information

  • ID HOM05D000602
  • #Genes/#Species 937/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT4G00570.1
  • symbol NAD-ME2
  • uniprot Q8L7K9

Descriptions

  • Description NAD-dependent malic enzyme 2
  • Computational description NAD-dependent malic enzyme 2 (NAD-ME2); FUNCTIONS IN: in 7 functions; INVOLVED IN: malate metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD-dependent malic enzyme 1 (TAIR:AT2G13560.1); Has 9343 Blast hits to 9326 proteins in 2439 species: Archae - 143; Bacteria - 6323; Metazoa - 607; Fungi - 223; Plants - 463; Viruses - 0; Other Eukaryotes - 1584 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006108
IDA
IBA
Gene Ontologymalate metabolic process1 2
GO:0006090
IBA
Gene Ontologypyruvate metabolic process2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004471
IEA
GOA Databasemalate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004471
IDA
IBA
Gene Ontologymalate dehydrogenase (decarboxylating) (NAD+) activity1 2
GO:0004471
IEA
InterPromalate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004470
IEA
GOA Databasemalic enzyme activity
GO:0004470
IBA
Gene Ontologymalic enzyme activity2
GO:0004470
IEA
InterPromalic enzyme activity
GO:0051287
IEA
Gene OntologyNAD binding
GO:0051287
IEA
InterProNAD binding
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0005524
IDA
GOA DatabaseATP binding
GO:0005524
HDA
Gene OntologyATP binding3
GO:0008270
IDA
GOA Databasezinc ion binding
GO:0008270
HDA
Gene Ontologyzinc ion binding4
GO:0050897
IDA
GOA Databasecobalt ion binding
GO:0050897
HDA
Gene Ontologycobalt ion binding4
GO:0005515
IPI
Gene Ontologyprotein binding5
GO:0042803
IDA
Gene Ontologyprotein homodimerization activity1
GO:0008948
IDA
Gene Ontologyoxaloacetate decarboxylase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005739
IDA
IEA
GOA Databasemitochondrion
GO:0005739
HDA
ISM, IBA
Gene Ontologymitochondrion2 6
GO:0005829
HDA
Gene Ontologycytosol7

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036291 NAD(P)-binding domain superfamily
IPR012302 Malic enzyme, NAD-binding
IPR012301 Malic enzyme, N-terminal domain
IPR001891 Malic oxidoreductase
IPR037062 Malic enzyme, N-terminal domain superfamily
Mapman id Description
2.3.9 Cellular respiration.tricarboxylic acid cycle.mitochondrial NAD-dependent malic enzyme