Gene: AT3G62770
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT3G62770
- Transcript Identifier AT3G62770.1
- Gene Type Coding gene
- Location Chr3 : 23218858-23221110 : negative
Gene Family Information
- ID HOM05D001050
- #Genes/#Species 579/100
- Phylogenetic origin
- ID ORTHO05D001270
- #Genes/#Species 443/99
- Phylogenetic origin
Gene Duplication Information
- Block Duplication Block duplicate
Labels
Identifiers
- tid AT3G62770.1
- symbol AtATG18a
- Alias ATG18a,autophagy 18a,PEUP2,PEROXISOME UNUSUAL POSITIONING 2
- full_name autophagy 18a
- uniprot Q93VB2
Descriptions
- Description Transducin/WD40 repeat-like superfamily protein
- Computational description AtATG18a; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: autophagy, leaf senescence, response to starvation; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: homolog of yeast autophagy 18 (ATG18) D (TAIR:AT3G56440.1); Has 1516 Blast hits to 1443 proteins in 266 species: Archae - 0; Bacteria - 93; Metazoa - 578; Fungi - 450; Plants - 210; Viruses - 2; Other Eukaryotes - 183 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0006497 | IBA | Gene Ontology | protein lipidation | 1 |
| GO:0044804 | IBA | Gene Ontology | autophagy of nucleus | 1 |
| GO:0000422 | IBA | Gene Ontology | autophagy of mitochondrion | 1 |
| GO:0034497 | IBA | Gene Ontology | protein localization to phagophore assembly site | 1 |
| GO:0006914 | IEA | GOA Database | autophagy | |
| GO:0006914 | IMP | Gene Ontology | autophagy | 2 |
| GO:0015031 | IEA | GOA Database | protein transport | |
| GO:0009414 | IMP, IEP | Gene Ontology | response to water deprivation | 3 4 |
| GO:0010508 | IMP | Gene Ontology | positive regulation of autophagy | 5 |
| GO:0050832 | IEP | Gene Ontology | defense response to fungus | 6 |
| GO:0009651 | IEP | Gene Ontology | response to salt stress | 3 |
| GO:0006970 | IEP | Gene Ontology | response to osmotic stress | 3 |
| GO:0006979 | IEP | Gene Ontology | response to oxidative stress | 7 |
| GO:0042594 | IMP, IEP | Gene Ontology | response to starvation | 2 |
| GO:0010150 | IMP | Gene Ontology | leaf senescence | 2 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0080025 | IBA | Gene Ontology | phosphatidylinositol-3,5-bisphosphate binding | 1 |
| GO:0032266 | IBA | Gene Ontology | phosphatidylinositol-3-phosphate binding | 1 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 6 |
| GO:0005515 | IEA | InterPro | protein binding |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005737 | IEA | GOA Database | cytoplasm | |
| GO:0019898 | IBA | Gene Ontology | extrinsic component of membrane | 1 |
| GO:0005774 | IEA | GOA Database | vacuolar membrane | |
| GO:0034045 | IEA | GOA Database | phagophore assembly site membrane | |
| GO:0034045 | IBA | Gene Ontology | phagophore assembly site membrane | 1 |
| GO:0005634 | IEA | GOA Database | nucleus | |
| GO:0005634 | IDA ISM | Gene Ontology | nucleus | 6 |
| GO:0005773 | IEA | GOA Database | vacuole | |
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0005829 | IDA IBA | Gene Ontology | cytosol | 1 6 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| Mapman id | Description |
|---|---|
| 19.3.3.5.1.3 | Protein homeostasis.autophagy.phagophore expansion.membrane shuttling.ATG9-2-18 membrane-recruiting complex.component ATG18 |