Gene: AT3G54660

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G54660
  • Transcript Identifier AT3G54660.1
  • Gene Type Coding gene
  • Location Chr3 : 20230356-20233100 : negative

Gene Family Information

  • ID HOM05D002220
  • #Genes/#Species 303/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G54660.1
  • symbol GR
  • Alias ATGR2,EMB2360
  • uniprot P42770

Descriptions

  • Description glutathione reductase
  • Computational description glutathione reductase (GR); FUNCTIONS IN: glutathione-disulfide reductase activity, copper ion binding, ATP binding; INVOLVED IN: glutathione metabolic process; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), FAD/NAD-linked reductase, dimerisation (InterPro:IPR016156), Pyridine nucleotide-disulphide oxidoreductase, class I, active site (InterPro:IPR012999), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327), Glutathione-disulphide reductase (InterPro:IPR006324), Pyridine nucleotide-disulphide oxidoreductase, dimerisation (InterPro:IPR004099); BEST Arabidopsis thaliana protein match is: glutathione-disulfide reductase (TAIR:AT3G24170.3); Has 33740 Blast hits to 33692 proteins in 3140 species: Archae - 759; Bacteria - 24408; Metazoa - 813; Fungi - 438; Plants - 579; Viruses - 0; Other Eukaryotes - 6743 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0045454
IEA
GOA Databasecell redox homeostasis
GO:0045454
IBA
Gene Ontologycell redox homeostasis1
GO:0045454
IEA
InterProcell redox homeostasis
GO:0098869
IEA
GOA Databasecellular oxidant detoxification
GO:0006749
IDA
IEA
Gene Ontologyglutathione metabolic process
GO:0006749
IEA
InterProglutathione metabolic process
GO:0006979
ISO
PLAZA Integrative Orthologyresponse to oxidative stress Zm00001eb004790
GO:0009631
ISO
PLAZA Integrative Orthologycold acclimation Zm00001eb004790
GO:0009635
ISO
PLAZA Integrative Orthologyresponse to herbicide Zm00001eb004790

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity
GO:0005524
IDA
GOA DatabaseATP binding
GO:0005524
HDA
Gene OntologyATP binding2
GO:0005507
IDA
GOA Databasecopper ion binding
GO:0005507
HDA
Gene Ontologycopper ion binding3
GO:0016668
IEA
GOA Databaseoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0050660
IEA
Gene Ontologyflavin adenine dinucleotide binding
GO:0050660
IEA
InterProflavin adenine dinucleotide binding
GO:0004362
IDA
IEA
Gene Ontologyglutathione-disulfide reductase (NADPH) activity
GO:0004362
IEA
InterProglutathione-disulfide reductase (NADPH) activity
GO:0050661
IEA
Gene OntologyNADP binding
GO:0050661
IEA
InterProNADP binding
GO:0004791
IBA
Gene Ontologythioredoxin-disulfide reductase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IDA
IEA
GOA Databasechloroplast
GO:0009507
HDA
ISS, ISM
Gene Ontologychloroplast4
GO:0009570
IDA
GOA Databasechloroplast stroma
GO:0009570
HDA
Gene Ontologychloroplast stroma5
GO:0009536
IEA
GOA Databaseplastid
GO:0005739
IDA, HDA
Gene Ontologymitochondrion2 6
GO:0005829
HDA
Gene Ontologycytosol7
GO:0005737
IBA
Gene Ontologycytoplasm1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR023753 FAD/NAD(P)-binding domain
IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily
IPR036188 FAD/NAD(P)-binding domain superfamily
IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I
IPR006324 Glutathione-disulphide reductase
Mapman id Description
10.5.4 Redox homeostasis.ascorbate-based redox regulation.glutathione reductase (GR)