Gene: AT3G24495

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G24495
  • Transcript Identifier AT3G24495.2
  • Gene Type Coding gene
  • Location Chr3 : 8913275-8918086 : negative

Gene Family Information

  • ID HOM05D001061
  • #Genes/#Species 575/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G24495.2
  • symbol MSH7
  • Alias ATMSH7,ARABIDOPSIS THALIANA MUTS HOMOLOG 7,MSH6-2,MUTS HOMOLOG 6-2
  • uniprot Q9SMV7

Descriptions

  • Description MUTS homolog 7
  • Computational description MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006298
IBA
IEA
Gene Ontologymismatch repair1
GO:0006298
IEA
InterPromismatch repair
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0000710
IBA
Gene Ontologymeiotic mismatch repair1
GO:0036297
IBA
Gene Ontologyinterstrand cross-link repair1
GO:0006290
IBA
Gene Ontologypyrimidine dimer repair1
GO:0043570
IBA
Gene Ontologymaintenance of DNA repeat elements1
GO:0045910
IBA
Gene Ontologynegative regulation of DNA recombination1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0030983
IBA
IEA
Gene Ontologymismatched DNA binding1
GO:0030983
IEA
InterPromismatched DNA binding
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0032357
IBA
Gene Ontologyoxidized purine DNA binding1
GO:0000400
IBA
Gene Ontologyfour-way junction DNA binding1
GO:0008094
IBA
Gene OntologyATPase, acting on DNA1
GO:0032405
IBA
Gene OntologyMutLalpha complex binding1
GO:0032143
IBA
Gene Ontologysingle thymine insertion binding1
GO:0005515
IPI
Gene Ontologyprotein binding2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0032301
IBA
Gene OntologyMutSalpha complex1
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0032300
IBA
Gene Ontologymismatch repair complex1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR007696 DNA mismatch repair protein MutS, core
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR045076 DNA mismatch repair MutS family
IPR007860 DNA mismatch repair protein MutS, connector domain
IPR036678 MutS, connector domain superfamily
IPR016151 DNA mismatch repair protein MutS, N-terminal
IPR036187 DNA mismatch repair protein MutS, core domain superfamily
IPR007695 DNA mismatch repair protein MutS-like, N-terminal
Mapman id Description
14.7.1.4 DNA damage response.mismatch repair (MMR).MSH2-x mismatch repair heterodimer components.component MSH7