Gene: AT3G24320

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G24320
  • Transcript Identifier AT3G24320.1
  • Gene Type Coding gene
  • Location Chr3 : 8823229-8829571 : negative

Gene Family Information

  • ID HOM05D004511
  • #Genes/#Species 160/92
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G24320.1
  • symbol MSH1
  • Alias ATMSH1,CHM1,CHM,CHLOROPLAST MUTATOR
  • uniprot Q84LK0

Descriptions

  • Description MUTL protein homolog 1
  • Computational description MUTL protein homolog 1 (MSH1); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, catalytic activity, ATP binding, nuclease activity; INVOLVED IN: mismatch repair, mitochondrial genome maintenance, mitochondrial DNA metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Serine/cysteine peptidase, trypsin-like (InterPro:IPR009003), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), Excinuclease ABC, C subunit, N-terminal (InterPro:IPR000305), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 14048 Blast hits to 12806 proteins in 2713 species: Archae - 218; Bacteria - 10179; Metazoa - 621; Fungi - 751; Plants - 393; Viruses - 3; Other Eukaryotes - 1883 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006298
IBA
IEA
Gene Ontologymismatch repair1
GO:0006298
IEA
InterPromismatch repair
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0000002
IMP, IGI
Gene Ontologymitochondrial genome maintenance2 3
GO:0009408
IGI
Gene Ontologyresponse to heat3
GO:0032042
IMP
Gene Ontologymitochondrial DNA metabolic process4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0008094
IBA
Gene OntologyATPase, acting on DNA1
GO:0030983
IBA
IEA
Gene Ontologymismatched DNA binding1
GO:0030983
IEA
InterPromismatched DNA binding
GO:0005524
IEA
Gene OntologyATP binding
GO:0005524
IEA
InterProATP binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IDA
Gene OntologyDNA binding5

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009536
IEA
GOA Databaseplastid
GO:0009536
IDA
Gene Ontologyplastid5
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA
Gene Ontologymitochondrion6
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA
Gene Ontologychloroplast6
GO:0032300
IBA
Gene Ontologymismatch repair complex1
GO:0042651
IDA
Gene Ontologythylakoid membrane5
GO:0005634
ISM
Gene Ontologynucleus

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR016151 DNA mismatch repair protein MutS, N-terminal
IPR045076 DNA mismatch repair MutS family
IPR035901 GIY-YIG endonuclease superfamily
IPR000432 DNA mismatch repair protein MutS, C-terminal
IPR000305 GIY-YIG endonuclease
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR007695 DNA mismatch repair protein MutS-like, N-terminal
Mapman id Description
13.5.8.5 Cell cycle organisation.organellar DNA replication.genome stability maintenance.regulatory factor (MSH1)