Gene: AT3G23890

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G23890
  • Transcript Identifier AT3G23890.1
  • Gene Type Coding gene
  • Location Chr3 : 8624931-8631106 : positive

Gene Family Information

  • ID HOM05D002263
  • #Genes/#Species 298/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G23890.1
  • symbol TOPII
  • Alias ATTOPII
  • uniprot P30182

Descriptions

  • Description topoisomerase II
  • Computational description topoisomerase II (TOPII); CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IIA, subunit A/C-terminal (InterPro:IPR002205), DNA topoisomerase, type IIA, conserved site (InterPro:IPR018522), DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta (InterPro:IPR013758), DNA topoisomerase, type IIA, subunit A, alpha-helical (InterPro:IPR013757), DNA topoisomerase, type IIA, subunit B, domain 2 (InterPro:IPR013506), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA topoisomerase, type IIA, subunit B/N-terminal, alpha-beta (InterPro:IPR013759), DNA topoisomerase, type IIA, subunit B/N-terminal (InterPro:IPR001241), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA topoisomerase II, eukaryotic-type (InterPro:IPR001154), DNA topoisomerase, type IIA, central (InterPro:IPR013760); BEST Arabidopsis thaliana protein match is: DNA GYRASE B2 (TAIR:AT5G04130.1); Has 46226 Blast hits to 43639 proteins in 5982 species: Archae - 169; Bacteria - 28615; Metazoa - 2871; Fungi - 1392; Plants - 616; Viruses - 201; Other Eukaryotes - 12362 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006259
IEA
GOA DatabaseDNA metabolic process
GO:0006259
IEA
InterProDNA metabolic process
GO:0006265
ISS
IEA
Gene OntologyDNA topological change
GO:0006265
IEA
InterProDNA topological change
GO:0000712
IBA
Gene Ontologyresolution of meiotic recombination intermediates1
GO:0000819
IBA
Gene Ontologysister chromatid segregation1
GO:0007059
ISS
Gene Ontologychromosome segregation

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0003918
ISS
IEA
Gene OntologyDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0003918
IEA
InterProDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016853
IEA
GOA Databaseisomerase activity
GO:0003916
IEA
GOA DatabaseDNA topoisomerase activity
GO:0003916
ISS
Gene OntologyDNA topoisomerase activity2
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0008094
ISS
Gene OntologyATPase, acting on DNA

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IDA
ISM, IBA
Gene Ontologynucleus1 3
GO:0009507
ISM
Gene Ontologychloroplast
GO:0009330
ISS
Gene OntologyDNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal
IPR003594 Histidine kinase/HSP90-like ATPase
IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal
IPR001154 DNA topoisomerase II, eukaryotic-type
IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily
IPR001241 DNA topoisomerase, type IIA
IPR013760 DNA topoisomerase, type IIA-like domain superfamily
IPR036890 Histidine kinase/HSP90-like ATPase superfamily
IPR031660 C-terminal associated domain of TOPRIM
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup
IPR006171 TOPRIM domain
IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta
IPR034157 DNA topoisomerase 2, TOPRIM domain
IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2
IPR020568 Ribosomal protein S5 domain 2-type fold
Mapman id Description
13.2.1.6 Cell cycle organisation.DNA replication.preinitiation.DNA topoisomerase (TOP2)