Gene: AT3G21250

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G21250
  • Transcript Identifier AT3G21250.3
  • Gene Type Coding gene
  • Location Chr3 : 7457668-7461809 : negative

Gene Family Information

  • ID HOM05D000121
  • #Genes/#Species 2804/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G21250.3
  • symbol ABCC8
  • Alias ATMRP6,ARABIDOPSIS THALIANA MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 6,MRP6,multidrug resistance-associated protein 6
  • full_name ATP-binding cassette C8
  • uniprot Q8LGU1

Descriptions

  • Description multidrug resistance-associated protein 6
  • Computational description multidrug resistance-associated protein 6 (MRP6); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to cyclopentenone; LOCATED IN: vacuolar membrane, plasma membrane, plant-type vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 14 (TAIR:AT3G59140.1); Has 598023 Blast hits to 338310 proteins in 3899 species: Archae - 10844; Bacteria - 482752; Metazoa - 12132; Fungi - 7443; Plants - 6523; Viruses - 16; Other Eukaryotes - 78313 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0055085
IBA
IEA
Gene Ontologytransmembrane transport1
GO:0055085
IEA
InterProtransmembrane transport
GO:0042908
IEA
GOA Databasexenobiotic transport

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0140359
IEA
Gene OntologyABC-type transporter activity
GO:0140359
IEA
InterProABC-type transporter activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0008559
IEA
Gene OntologyABC-type xenobiotic transporter activity
GO:0042626
ISS, IBA
Gene OntologyATPase-coupled transmembrane transporter activity1 2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000325
IDA
GOA Databaseplant-type vacuole
GO:0000325
HDA
IBA
Gene Ontologyplant-type vacuole1 3
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0016021
IEA
InterProintegral component of membrane
GO:0005774
IDA
GOA Databasevacuolar membrane
GO:0005774
HDA
IBA
Gene Ontologyvacuolar membrane1 3
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IBA
Gene Ontologymembrane1
GO:0005829
HDA
Gene Ontologycytosol4
GO:0009507
ISM
Gene Ontologychloroplast

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR044726 ABC transporter C family, six-transmembrane helical domain 2
IPR011527 ABC transporter type 1, transmembrane domain
IPR003439 ABC transporter-like, ATP-binding domain
IPR036640 ABC transporter type 1, transmembrane domain superfamily
IPR003593 AAA+ ATPase domain
Mapman id Description
24.1.3.1.2 Solute transport.primary active transport.ABC superfamily.ABC1 family.subfamily ABCC transporter