Gene: AT3G10160

General Information

tid AT3G10160.1
symbol DFC
Alias ATDFC,A. THALIANA DHFS-FPGS HOMOLOG C,FPGS2,folylpolyglutamate synthetase 2
uniprot F4J2K2

Computational description DHFS-FPGS homolog C (DFC); CONTAINS InterPro DOMAIN/s: Mur ligase, central (InterPro:IPR013221), Folylpolyglutamate synthetase, conserved site (InterPro:IPR018109), Mur ligase, C-terminal (InterPro:IPR004101), Folylpolyglutamate synthetase (InterPro:IPR001645); BEST Arabidopsis thaliana protein match is: DHFS-FPGS homolog B (TAIR:AT5G05980.2); Has 7721 Blast hits to 7719 proteins in 2542 species: Archae - 43; Bacteria - 4847; Metazoa - 165; Fungi - 368; Plants - 133; Viruses - 0; Other Eukaryotes - 2165 (source: NCBI BLink).

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0009058	IEA	GOA Database	biosynthetic process
GO:0009058	IEA	InterPro	biosynthetic process
GO:0009396	IEA	GOA Database	folic acid-containing compound biosynthetic process
GO:0009396	IBA	Gene Ontology	folic acid-containing compound biosynthetic process	1
GO:0009396	IEA	InterPro	folic acid-containing compound biosynthetic process
GO:0006730	IEA	GOA Database	one-carbon metabolic process
GO:0006730	TAS	Gene Ontology	one-carbon metabolic process	2
GO:0046901	IBA IEA	Gene Ontology	tetrahydrofolylpolyglutamate biosynthetic process	1
GO:0090351	IMP	Gene Ontology	seedling development	3
GO:0009853	IMP	Gene Ontology	photorespiration	3

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0016874	IEA	GOA Database	ligase activity
GO:0016874	IEA	InterPro	ligase activity
GO:0005524	IEA	GOA Database	ATP binding
GO:0005524	IEA	InterPro	ATP binding
GO:0004326	IEA	GOA Database	tetrahydrofolylpolyglutamate synthase activity
GO:0004326	IMP, IGI IBA	Gene Ontology	tetrahydrofolylpolyglutamate synthase activity	1 2 4
GO:0004326	IEA	InterPro	tetrahydrofolylpolyglutamate synthase activity
GO:0000166	IEA	GOA Database	nucleotide binding
GO:0046872	IEA	GOA Database	metal ion binding

GO term	Evidence(s)	Provider(s)	Description	Source(s)
GO:0005743	IEA	GOA Database	mitochondrial inner membrane
GO:0016020	IEA	GOA Database	membrane
GO:0005739	IEA	GOA Database	mitochondrion
GO:0005739	IBA	Gene Ontology	mitochondrion	1
GO:0005759	IEA	GOA Database	mitochondrial matrix
GO:0005759	IDA	Gene Ontology	mitochondrial matrix	2
GO:0005829	IBA	Gene Ontology	cytosol	1
GO:0005737	IBA	Gene Ontology	cytoplasm	1

Experimental Evidence

Computational Reviewed Evidence

Electronic Evidence

InterPro	Description
IPR001645	Folylpolyglutamate synthetase
IPR036615	Mur ligase, C-terminal domain superfamily
IPR036565	Mur-like, catalytic domain superfamily

Mapman id	Description
7.5.6	Coenzyme metabolism.tetrahydrofolate metabolism.folyl-polyglutamate synthetase