Gene: AT3G06370

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G06370
  • Transcript Identifier AT3G06370.2
  • Gene Type Coding gene
  • Location Chr3 : 1931441-1933515 : negative

Gene Family Information

  • ID HOM05D000735
  • #Genes/#Species 795/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G06370.2
  • symbol NHX4
  • Alias ATNHX4
  • uniprot Q84WG1

Descriptions

  • Description sodium hydrogen exchanger 4
  • Computational description sodium hydrogen exchanger 4 (NHX4); FUNCTIONS IN: sodium:hydrogen antiporter activity, sodium ion transmembrane transporter activity; INVOLVED IN: response to salt stress, sodium ion transport; LOCATED IN: vacuolar membrane, plasma membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Na /H exchanger, subfamily (InterPro:IPR004709), Cation/H exchanger, conserved region (InterPro:IPR018422), Cation/H exchanger (InterPro:IPR006153), Na /H exchanger, isoforms 1-4, conserved region (InterPro:IPR018407); BEST Arabidopsis thaliana protein match is: sodium hydrogen exchanger 2 (TAIR:AT3G05030.1); Has 5892 Blast hits to 5885 proteins in 1663 species: Archae - 61; Bacteria - 4002; Metazoa - 840; Fungi - 131; Plants - 419; Viruses - 0; Other Eukaryotes - 439 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006885
IEA
Gene Ontologyregulation of pH
GO:0006885
IEA
InterProregulation of pH
GO:0006814
IEA
GOA Databasesodium ion transport
GO:0006814
IEA
InterProsodium ion transport
GO:0055085
IEA
GOA Databasetransmembrane transport
GO:0055085
IEA
InterProtransmembrane transport
GO:0006812
IEA
GOA Databasecation transport
GO:0006812
IEA
InterProcation transport
GO:0006811
IEA
GOA Databaseion transport
GO:0098656
IEA
GOA Databaseanion transmembrane transport
GO:1902600
IEA
GOA Databaseproton transmembrane transport
GO:0051453
IBA
Gene Ontologyregulation of intracellular pH1
GO:0098719
IBA
Gene Ontologysodium ion import across plasma membrane1
GO:0071805
IBA
Gene Ontologypotassium ion transmembrane transport1
GO:0009651
IMP
Gene Ontologyresponse to salt stress2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0015385
IBA
IEA
Gene Ontologysodium:proton antiporter activity1
GO:0015385
IEA
InterProsodium:proton antiporter activity
GO:0015299
IEA
GOA Databasesolute:proton antiporter activity
GO:0015299
IEA
InterProsolute:proton antiporter activity
GO:0015297
IEA
GOA Databaseantiporter activity
GO:0015386
IBA
Gene Ontologypotassium:proton antiporter activity1
GO:0015081
ISS
Gene Ontologysodium ion transmembrane transporter activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005773
IEA
GOA Databasevacuole
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0016021
IEA
InterProintegral component of membrane
GO:0016020
IEA
GOA Databasemembrane
GO:0005774
IEA
GOA Databasevacuolar membrane
GO:0005774
IDA
Gene Ontologyvacuolar membrane2
GO:0005886
IBA
Gene Ontologyplasma membrane1
GO:0000325
HDA
Gene Ontologyplant-type vacuole3
GO:0009507
ISM
Gene Ontologychloroplast

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR006153 Cation/H+ exchanger
IPR018422 Cation/H+ exchanger, CPA1 family
IPR004709 Na+/H+ exchanger
Mapman id Description
24.2.8.1.1 Solute transport.carrier-mediated transport.CPA superfamily.CPA-1 family.proton:cation antiporter (NHX)