Gene: AT3G06060

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT3G06060
  • Transcript Identifier AT3G06060.2
  • Gene Type Coding gene
  • Location Chr3 : 1828296-1830211 : negative

Gene Family Information

  • ID HOM05D003236
  • #Genes/#Species 212/94
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT3G06060.2
  • symbol TSC10A
  • uniprot Q0WRJ2

Descriptions

  • Description NAD(P)-binding Rossmann-fold superfamily protein
  • Computational description NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: oxidoreductase activity, binding, catalytic activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT5G19200.1); Has 110611 Blast hits to 110370 proteins in 3576 species: Archae - 917; Bacteria - 74698; Metazoa - 5725; Fungi - 6415; Plants - 2635; Viruses - 0; Other Eukaryotes - 20221 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006665
IEA
GOA Databasesphingolipid metabolic process
GO:0030148
IMP
IBA
IEA
Gene Ontologysphingolipid biosynthetic process1 2
GO:0030148
IEA
InterProsphingolipid biosynthetic process
GO:0006666
IBA
IEA
Gene Ontology3-keto-sphinganine metabolic process2
GO:0006666
IEA
InterPro3-keto-sphinganine metabolic process
GO:0006629
IEA
GOA Databaselipid metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0047560
IDA
IBA
IEA
Gene Ontology3-dehydrosphinganine reductase activity1 2
GO:0047560
IEA
InterPro3-dehydrosphinganine reductase activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IEA
InterProoxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005783
IEA
GOA Databaseendoplasmic reticulum
GO:0016020
IEA
GOA Databasemembrane
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane
GO:0005789
IDA
IBA
Gene Ontologyendoplasmic reticulum membrane1 2
GO:0009507
ISM
Gene Ontologychloroplast

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR002347 Short-chain dehydrogenase/reductase SDR
IPR045022 3-ketodihydrosphingosine reductase KDSR-like
IPR036291 NAD(P)-binding domain superfamily
Mapman id Description
5.4.3 Lipid metabolism.sphingolipid biosynthesis.ketosphinganine reductase (TSC10)