Gene: AT2G44160

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G44160
  • Transcript Identifier AT2G44160.1
  • Gene Type Coding gene
  • Location Chr2 : 18262301-18265185 : positive

Gene Family Information

  • ID HOM05D003257
  • #Genes/#Species 210/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G44160.1
  • symbol MTHFR2
  • uniprot O80585

Descriptions

  • Description methylenetetrahydrofolate reductase 2
  • Computational description methylenetetrahydrofolate reductase 2 (MTHFR2); FUNCTIONS IN: methylenetetrahydrofolate reductase (NADPH) activity; INVOLVED IN: oxidation reduction, methionine metabolic process; EXPRESSED IN: male gametophyte, guard cell, cultured cell, leaf; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Methylenetetrahydrofolate reductase (InterPro:IPR003171), Eukaryotic-type methylenetetrahydrofolate reductase (InterPro:IPR004621); BEST Arabidopsis thaliana protein match is: methylenetetrahydrofolate reductase 1 (TAIR:AT3G59970.3); Has 4605 Blast hits to 4574 proteins in 1845 species: Archae - 16; Bacteria - 3444; Metazoa - 135; Fungi - 300; Plants - 75; Viruses - 0; Other Eukaryotes - 635 (source: NCBI BLink).
  • Loading (ortholog descriptions from ath)...

Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0035999
IBA
IEA
Gene Ontologytetrahydrofolate interconversion1
GO:0009086
IBA
Gene Ontologymethionine biosynthetic process1
GO:0006555
IEA
GOA Databasemethionine metabolic process
GO:0006555
IEA
InterPromethionine metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0071949
IBA
Gene OntologyFAD binding1
GO:0004489
IEA
GOA Databasemethylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0004489
IBA
Gene Ontologymethylenetetrahydrofolate reductase (NAD(P)H) activity1
GO:0004489
IEA
InterPromethylenetetrahydrofolate reductase (NAD(P)H) activity
GO:0106313
IEA
GOA Databasemethylenetetrahydrofolate reductase NADPH activity
GO:0106312
IEA
GOA Databasemethylenetetrahydrofolate reductase NADH activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
ISM
Gene Ontologynucleus
GO:0005829
IDA
GOA Databasecytosol
GO:0005829
HDA
IBA
Gene Ontologycytosol1 2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR029041 FAD-linked oxidoreductase-like
IPR003171 Methylenetetrahydrofolate reductase-like
IPR004621 Eukaryotic-type methylenetetrahydrofolate reductase
Mapman id Description
7.5.7.4 Coenzyme metabolism.tetrahydrofolate metabolism.tetrahydrofolate (THF) interconversions.5,10-methylene-THF reductase