Gene: AT2G43420

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G43420
  • Transcript Identifier AT2G43420.1
  • Gene Type Coding gene
  • Location Chr2 : 18031493-18034936 : negative

Gene Family Information

  • ID HOM05D002028
  • #Genes/#Species 326/99
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G43420.1
  • uniprot A9X4U2

Descriptions

  • Description 3-beta hydroxysteroid dehydrogenase/isomerase family protein
  • Computational description 3-beta hydroxysteroid dehydrogenase/isomerase family protein; FUNCTIONS IN: binding, 3-beta-hydroxy-delta5-steroid dehydrogenase activity, catalytic activity; INVOLVED IN: steroid biosynthetic process, metabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Reticulon (InterPro:IPR003388), 3-beta hydroxysteroid dehydrogenase/isomerase (InterPro:IPR002225), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: 3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform 2 (TAIR:AT2G26260.1); Has 10307 Blast hits to 10296 proteins in 2122 species: Archae - 301; Bacteria - 6803; Metazoa - 545; Fungi - 280; Plants - 752; Viruses - 81; Other Eukaryotes - 1545 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006694
IEA
GOA Databasesteroid biosynthetic process
GO:0006694
IEA
InterProsteroid biosynthetic process
GO:0016126
IEA
GOA Databasesterol biosynthetic process
GO:0008202
IEA
GOA Databasesteroid metabolic process
GO:0006629
IEA
GOA Databaselipid metabolic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016616
IEA
GOA Databaseoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016616
IBA
Gene Ontologyoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor1
GO:0016616
IEA
InterProoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0003854
IEA
Gene Ontology3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0003854
IEA
InterPro3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0000252
IEA
Gene OntologyC-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity
GO:0102175
IEA
GOA Database3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase activity
GO:0005515
IPI
Gene Ontologyprotein binding2
GO:0103067
IEA
Gene Ontology4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity
GO:0103066
IEA
Gene Ontology4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity
GO:0047012
IEA
Gene Ontologysterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009506
IDA
GOA Databaseplasmodesma
GO:0009506
HDA
Gene Ontologyplasmodesma3
GO:0005783
IEA
GOA Databaseendoplasmic reticulum
GO:0005783
IDA
Gene Ontologyendoplasmic reticulum2
GO:0016020
IEA
GOA Databasemembrane
GO:0016021
IEA
GOA Databaseintegral component of membrane
GO:0005886
IDA
GOA Databaseplasma membrane
GO:0005789
IEA
GOA Databaseendoplasmic reticulum membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR003388 Reticulon
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR036291 NAD(P)-binding domain superfamily
Mapman id Description
5.5.2.3 Lipid metabolism.phytosterol biosynthesis.phytosterol C4-demethylation complex.3-beta hydroxysteroid dehydrogenase component CSD