Gene: AT2G38050

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G38050
  • Transcript Identifier AT2G38050.1
  • Gene Type Coding gene
  • Location Chr2 : 15921303-15922176 : negative

Gene Family Information

  • ID HOM05D006607
  • #Genes/#Species 121/92
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G38050.1
  • symbol DET2
  • Alias ATDET2,DWF6,DWARF 6
  • full_name DE-ETIOLATED 2
  • uniprot Q38944

Descriptions

  • Description 3-oxo-5-alpha-steroid 4-dehydrogenase family protein
  • Computational description DE-ETIOLATED 2 (DET2); FUNCTIONS IN: sterol 5-alpha reductase activity; INVOLVED IN: response to light stimulus, brassinosteroid homeostasis, brassinosteroid biosynthetic process; LOCATED IN: endomembrane system, integral to membrane, membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104), 3-oxo-5-alpha-steroid 4-dehydrogenase (InterPro:IPR016636); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT5G16010.1); Has 1601 Blast hits to 1599 proteins in 320 species: Archae - 0; Bacteria - 193; Metazoa - 442; Fungi - 195; Plants - 239; Viruses - 0; Other Eukaryotes - 532 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009414
ISO
PLAZA Integrative Orthologyresponse to water deprivation Solyc10g086500.1
GO:0006629
IEA
GOA Databaselipid metabolic process
GO:0006629
IEA
InterProlipid metabolic process
GO:0008202
IEA
GOA Databasesteroid metabolic process
GO:0008202
IEA
InterProsteroid metabolic process
GO:0006694
IEA
GOA Databasesteroid biosynthetic process
GO:0016132
IDA, IMP
IBA
IEA
Gene Ontologybrassinosteroid biosynthetic process1 2 3
GO:0009416
TAS
Gene Ontologyresponse to light stimulus1
GO:0010268
IEP
Gene Ontologybrassinosteroid homeostasis4

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016627
IEA
GOA Databaseoxidoreductase activity, acting on the CH-CH group of donors
GO:0016627
IEA
InterProoxidoreductase activity, acting on the CH-CH group of donors
GO:0003865
IEA
Gene Ontology3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0003865
IEA
InterPro3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0016491
IBA
Gene Ontologyoxidoreductase activity3
GO:0050213
IDA, IMP
Gene Ontologyprogesterone 5-alpha-reductase activity5 6
GO:0009917
IDA
Gene Ontologysterol 5-alpha reductase activity2
GO:0047751
IEA
Gene Ontologycholestenone 5-alpha-reductase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016020
IEA
GOA Databasemembrane
GO:0016020
IEA
InterPromembrane
GO:0016021
IEA
GOA Databaseintegral component of membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR016636 3-oxo-5-alpha-steroid 4-dehydrogenase
IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
IPR039357 3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase
Mapman id Description
11.3.1.3 Phytohormone action.brassinosteroid.biosynthesis.steroid 5-alpha-reductase (DET2)