Gene: AT2G34660
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT2G34660
- Transcript Identifier AT2G34660.2
- Gene Type Coding gene
- Location Chr2 : 14603267-14612387 : positive
Gene Family Information
- ID HOM05D000121
- #Genes/#Species 2804/100
- Phylogenetic origin
- ID ORTHO05D001726
- #Genes/#Species 364/95
- Phylogenetic origin
Gene Duplication Information
- Block Duplication Block duplicate
Labels
Identifiers
- tid AT2G34660.2
- symbol ABCC2
- Alias ATMRP2,multidrug resistance-associated protein 2,AtABCC2,Arabidopsis thaliana ATP-binding cassette C2,EST4,MRP2,multidrug resistance-associated protein 2
- full_name ATP-binding cassette C2
- uniprot Q42093
Descriptions
- Description multidrug resistance-associated protein 2
- Computational description multidrug resistance-associated protein 2 (MRP2); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: response to cyclopentenone; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2); Has 677853 Blast hits to 353182 proteins in 3940 species: Archae - 12495; Bacteria - 548354; Metazoa - 12805; Fungi - 8204; Plants - 5931; Viruses - 21; Other Eukaryotes - 90043 (source: NCBI BLink).
- Computational description multidrug resistance-associated protein 2 (MRP2); CONTAINS InterPro DOMAIN/s: ATPase, AAA type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 1 (TAIR:AT1G30400.2).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0055085 | IDA IBA IEA | Gene Ontology | transmembrane transport | 1 2 |
| GO:0055085 | IEA | InterPro | transmembrane transport | |
| GO:0042908 | IEA | GOA Database | xenobiotic transport | |
| GO:1902418 | IDA | Gene Ontology | (+)-abscisic acid D-glucopyranosyl ester transmembrane transport | 3 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0140359 | IEA | Gene Ontology | ABC-type transporter activity | |
| GO:0140359 | IEA | InterPro | ABC-type transporter activity | |
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0005524 | IEA | InterPro | ATP binding | |
| GO:0005516 | IEA | GOA Database | calmodulin binding | |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0008559 | IEA | Gene Ontology | ABC-type xenobiotic transporter activity | |
| GO:0042626 | IDA ISS, IBA | Gene Ontology | ATPase-coupled transmembrane transporter activity | 1 2 4 |
| GO:1902417 | IDA | Gene Ontology | (+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity | 3 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016021 | IEA | GOA Database | integral component of membrane | |
| GO:0016021 | IEA | InterPro | integral component of membrane | |
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0016020 | IBA | Gene Ontology | membrane | 2 |
| GO:0005773 | IDA IEA | GOA Database | vacuole | |
| GO:0005773 | HDA | Gene Ontology | vacuole | 5 |
| GO:0000325 | IDA | GOA Database | plant-type vacuole | |
| GO:0000325 | HDA IBA | Gene Ontology | plant-type vacuole | 2 6 |
| GO:0005774 | IDA IEA | GOA Database | vacuolar membrane | |
| GO:0005774 | HDA IBA | Gene Ontology | vacuolar membrane | 2 6 |
| GO:0005783 | HDA | Gene Ontology | endoplasmic reticulum | 7 |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| IPR036640 | ABC transporter type 1, transmembrane domain superfamily |
| IPR044726 | ABC transporter C family, six-transmembrane helical domain 2 |
| IPR003439 | ABC transporter-like, ATP-binding domain |
| IPR011527 | ABC transporter type 1, transmembrane domain |
| IPR044746 | ABC transporter C family, six-transmembrane helical domain 1 |
| IPR003593 | AAA+ ATPase domain |
| Mapman id | Description |
|---|---|
| 24.1.3.1.2 | Solute transport.primary active transport.ABC superfamily.ABC1 family.subfamily ABCC transporter |
| 26.7.2.4.1 | External stimuli response.toxic compounds.arsenic.vacuolar sequestration.glutathione S-conjugate transporter |