Gene: AT2G22450

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G22450
  • Transcript Identifier AT2G22450.1
  • Gene Type Coding gene
  • Location Chr2 : 9530654-9532691 : positive

Gene Family Information

  • ID HOM05D000723
  • #Genes/#Species 800/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G22450.1
  • symbol RIBA2
  • Alias AtRIBA2
  • full_name homolog of ribA 2
  • uniprot Q6NLQ7

Descriptions

  • Description riboflavin biosynthesis protein
  • Computational description riboflavin biosynthesis protein, putative; FUNCTIONS IN: 3,4-dihydroxy-2-butanone-4-phosphate synthase activity, GTP cyclohydrolase II activity; INVOLVED IN: riboflavin biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP cyclohydrolase II (InterPro:IPR000926), Riboflavin biosynthesis protein RibA (InterPro:IPR016299), DHBP synthase RibB (InterPro:IPR000422), DHBP synthase RibB-like alpha/beta domain (InterPro:IPR017945); BEST Arabidopsis thaliana protein match is: GTP cyclohydrolase II (TAIR:AT5G64300.1); Has 11284 Blast hits to 11282 proteins in 2317 species: Archae - 207; Bacteria - 6851; Metazoa - 1; Fungi - 301; Plants - 119; Viruses - 0; Other Eukaryotes - 3805 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006412
ISO
PLAZA Homology (enrichment)translation HOM05D000723
GO:0009231
IBA
IEA
Gene Ontologyriboflavin biosynthetic process1
GO:0009231
IEA
InterProriboflavin biosynthetic process

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0003735
ISO
PLAZA Homology (enrichment)structural constituent of ribosome HOM05D000723
GO:0008686
IEA
GOA Database3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0008686
IDA
IBA
Gene Ontology3,4-dihydroxy-2-butanone-4-phosphate synthase activity1 2
GO:0008686
IEA
InterPro3,4-dihydroxy-2-butanone-4-phosphate synthase activity
GO:0005525
IEA
GOA DatabaseGTP binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016829
IEA
GOA Databaselyase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0003935
IDA
Gene OntologyGTP cyclohydrolase II activity2

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0009507
IEA
GOA Databasechloroplast
GO:0009507
IDA, HDA
IBA
Gene Ontologychloroplast1 2 3
GO:0005840
ISO
PLAZA Homology (enrichment)ribosome HOM05D000723
GO:0009536
IEA
GOA Databaseplastid
GO:0005886
ISM
Gene Ontologyplasma membrane

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB
IPR032677 GTP cyclohydrolase II
IPR036144 GTP cyclohydrolase II superfamily
IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily
Mapman id Description
50.3.5 Enzyme classification.EC_3 hydrolases.EC_3.5 hydrolase acting on carbon-nitrogen bond, other than peptide bond