Gene: AT2G19900

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G19900
  • Transcript Identifier AT2G19900.1
  • Gene Type Coding gene
  • Location Chr2 : 8592106-8595403 : negative

Gene Family Information

  • ID HOM05D000602
  • #Genes/#Species 937/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G19900.1
  • symbol NADP-ME1
  • Alias ATNADP-ME1,Arabidopsis thaliana NADP-malic enzyme 1
  • uniprot O82191

Descriptions

  • Description NADP-malic enzyme 1
  • Computational description NADP-malic enzyme 1 (NADP-ME1); FUNCTIONS IN: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP ) activity, oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor, malic enzyme activity; INVOLVED IN: malate metabolic process, protein homooligomerization; LOCATED IN: cytosol; EXPRESSED IN: embryo, sperm cell, root, stamen, seed; EXPRESSED DURING: 4 anthesis, D bilateral stage; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NADP-malic enzyme 3 (TAIR:AT5G25880.1); Has 9392 Blast hits to 9373 proteins in 2414 species: Archae - 143; Bacteria - 6244; Metazoa - 609; Fungi - 220; Plants - 469; Viruses - 0; Other Eukaryotes - 1707 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006108
IDA
IBA
Gene Ontologymalate metabolic process1 2
GO:0006090
IBA
Gene Ontologypyruvate metabolic process2

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0004470
IEA
GOA Databasemalic enzyme activity
GO:0004470
IBA
Gene Ontologymalic enzyme activity2
GO:0004470
IEA
InterPromalic enzyme activity
GO:0051287
IEA
Gene OntologyNAD binding
GO:0051287
IEA
InterProNAD binding
GO:0004471
IEA
Gene Ontologymalate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004471
IEA
InterPromalate dehydrogenase (decarboxylating) (NAD+) activity
GO:0016491
IEA
GOA Databaseoxidoreductase activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0004473
IEA
GOA Databasemalate dehydrogenase (decarboxylating) (NADP+) activity
GO:0004473
IDA
IBA
Gene Ontologymalate dehydrogenase (decarboxylating) (NADP+) activity1 2
GO:0008948
IEA
Gene Ontologyoxaloacetate decarboxylase activity

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
ISM
Gene Ontologycytoplasm
GO:0009507
IBA
Gene Ontologychloroplast2
GO:0005739
HDA
Gene Ontologymitochondrion3
GO:0005829
NAS
Gene Ontologycytosol1

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036291 NAD(P)-binding domain superfamily
IPR012301 Malic enzyme, N-terminal domain
IPR012302 Malic enzyme, NAD-binding
IPR001891 Malic oxidoreductase
IPR037062 Malic enzyme, N-terminal domain superfamily
Mapman id Description
5.1.1.4 Lipid metabolism.fatty acid biosynthesis.citrate shuttle.cytosolic NADP-dependent malic enzyme