Gene: AT2G16485

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G16485
  • Transcript Identifier AT2G16485.2
  • Gene Type Coding gene
  • Location Chr2 : 7137269-7145222 : negative

Gene Family Information

  • ID HOM05D000706
  • #Genes/#Species 813/97
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G16485.2
  • symbol NERD
  • full_name Needed for RDR2-independent DNA methylation
  • uniprot Q9SIV5

Descriptions

  • Description GW repeat- and PHD finger-containing protein NERD
  • Computational description nucleic acid binding;zinc ion binding;DNA binding; FUNCTIONS IN: DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: histone modification, transcription initiation; LOCATED IN: nucleus; EXPRESSED IN: guard cell, cultured cell; CONTAINS InterPro DOMAIN/s: Zinc finger, CCCH-type (InterPro:IPR000571), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Plus-3 domain, subgroup (InterPro:IPR018144), Zinc finger, PHD-type (InterPro:IPR001965), GYF (InterPro:IPR003169), SWIB/MDM2 domain (InterPro:IPR003121), Plus-3 (InterPro:IPR004343), SWIB domain (InterPro:IPR019835), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: DNA binding;zinc ion binding;nucleic acid binding;nucleic acid binding (TAIR:AT3G51120.1); Has 38357 Blast hits to 25980 proteins in 1833 species: Archae - 670; Bacteria - 4778; Metazoa - 14464; Fungi - 4561; Plants - 3104; Viruses - 298; Other Eukaryotes - 10482 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0031047
IEA
GOA Databasegene silencing by RNA
GO:0032776
IMP
Gene OntologyDNA methylation on cytosine1
GO:0010964
IDA
Gene Ontologyregulation of heterochromatin assembly by small RNA1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005515
IPI
Gene Ontologyprotein binding1
GO:0005515
IEA
InterProprotein binding
GO:0003677
IEA
Gene OntologyDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0046872
IEA
InterPrometal ion binding
GO:1990269
IBA
Gene OntologyRNA polymerase II C-terminal domain phosphoserine binding2
GO:0042393
IDA
Gene Ontologyhistone binding1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0016593
IBA
Gene OntologyCdc73/Paf1 complex2
GO:0005829
IDA
GOA Databasecytosol
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
ISM
Gene Ontologynucleus1
GO:0005737
ISM
Gene Ontologycytoplasm

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR013083 Zinc finger, RING/FYVE/PHD-type
IPR000571 Zinc finger, CCCH-type
IPR004343 Plus-3 domain
IPR003121 SWIB/MDM2 domain
IPR003169 GYF domain
IPR036885 SWIB/MDM2 domain superfamily
IPR035445 GYF-like domain superfamily
IPR011011 Zinc finger, FYVE/PHD-type
IPR019835 SWIB domain
IPR001965 Zinc finger, PHD-type
IPR036128 Plus3-like superfamily
Mapman id Description
12.5.1.15.1 Chromatin organisation.DNA methylation.RNA-directed DNA methylation (RdDM) pathway.non-canonical RdDM pathway.protein factor (NERD)