Gene: AT2G07690

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT2G07690
  • Transcript Identifier AT2G07690.1
  • Gene Type Coding gene
  • Location Chr2 : 3523379-3527388 : negative

Gene Family Information

  • ID HOM05D000361
  • #Genes/#Species 1321/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT2G07690.1
  • symbol MCM5
  • full_name MINICHROMOSOME MAINTENANCE 5
  • uniprot O80786

Descriptions

  • Description Minichromosome maintenance (MCM2/3/5) family protein
  • Computational description MINICHROMOSOME MAINTENANCE 5 (MCM5); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin, nucleus, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 5 (InterPro:IPR008048); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 3980 Blast hits to 3841 proteins in 547 species: Archae - 376; Bacteria - 145; Metazoa - 1209; Fungi - 933; Plants - 431; Viruses - 3; Other Eukaryotes - 883 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
IEA
GOA DatabaseDNA replication
GO:0007049
IEA
GOA Databasecell cycle
GO:0006270
IBA
IEA
Gene OntologyDNA replication initiation1
GO:0006270
IEA
InterProDNA replication initiation
GO:0006267
IBA
GOA Databasepre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0032508
IEA
Gene OntologyDNA duplex unwinding
GO:0032508
IEA
InterProDNA duplex unwinding
GO:0006268
TAS
Gene OntologyDNA unwinding involved in DNA replication2
GO:0000727
IBA
Gene Ontologydouble-strand break repair via break-induced replication1

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0003677
IEA
GOA DatabaseDNA binding
GO:0003677
IEA
InterProDNA binding
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0016787
IEA
GOA Databasehydrolase activity
GO:0004386
IEA
GOA Databasehelicase activity
GO:0003688
IEA
Gene OntologyDNA replication origin binding
GO:0003688
IEA
InterProDNA replication origin binding
GO:0005515
IPI
Gene Ontologyprotein binding3
GO:0003678
IEA
Gene OntologyDNA helicase activity
GO:0043138
IBA
Gene Ontology3'-5' DNA helicase activity1
GO:0003697
IBA
Gene Ontologysingle-stranded DNA binding1
GO:0017116
IBA
Gene Ontologysingle-stranded DNA helicase activity1

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005737
IEA
GOA Databasecytoplasm
GO:0005737
IDA
Gene Ontologycytoplasm2
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
ISM, IBA
Gene Ontologynucleus1 2
GO:0005634
IEA
InterPronucleus
GO:0042555
IBA
IEA
Gene OntologyMCM complex1
GO:0042555
IEA
InterProMCM complex
GO:0000347
IDA
Gene OntologyTHO complex3
GO:0000785
IDA
Gene Ontologychromatin2

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR001208 MCM domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
IPR008048 DNA replication licensing factor Mcm5
IPR027925 MCM N-terminal domain
IPR012340 Nucleic acid-binding, OB-fold
IPR033762 MCM OB domain
IPR041562 MCM, AAA-lid domain
IPR031327 Mini-chromosome maintenance protein
Mapman id Description
13.2.1.2.4 Cell cycle organisation.DNA replication.preinitiation.MCM replicative DNA helicase complex.component MCM5