Gene: AT1G66730

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G66730
  • Transcript Identifier AT1G66730.1
  • Gene Type Coding gene
  • Location Chr1 : 24884991-24891823 : positive

Gene Family Information

  • ID HOM05D001934
  • #Genes/#Species 342/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G66730.1
  • symbol LIG6
  • Alias AtLIG6,DNA LIGASE 6
  • uniprot F4HPZ9

Descriptions

  • Description DNA LIGASE 6
  • Computational description DNA LIGASE 6 (LIG6); FUNCTIONS IN: DNA binding, DNA ligase (ATP) activity, ATP binding; INVOLVED IN: DNA repair, seed germination, DNA recombination, DNA replication; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA ligase, N-terminal (InterPro:IPR012308), DNA repair metallo-beta-lactamase (InterPro:IPR011084), ATP dependent DNA ligase, central (InterPro:IPR012310), ATP dependent DNA ligase, C-terminal (InterPro:IPR012309), ATP-dependent DNA ligase (InterPro:IPR000977), ATP-dependent DNA ligase, conserved site (InterPro:IPR016059); BEST Arabidopsis thaliana protein match is: DNA ligase 1 (TAIR:AT1G08130.1); Has 4468 Blast hits to 4373 proteins in 907 species: Archae - 366; Bacteria - 1648; Metazoa - 644; Fungi - 681; Plants - 268; Viruses - 157; Other Eukaryotes - 704 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0006260
IEA
GOA DatabaseDNA replication
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IMP
Gene OntologyDNA repair1
GO:0006281
IEA
InterProDNA repair
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0006310
IEA
InterProDNA recombination
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0071897
IEA
Gene OntologyDNA biosynthetic process
GO:0071897
IEA
InterProDNA biosynthetic process
GO:0048316
IMP
Gene Ontologyseed development1
GO:0010225
IDA
Gene Ontologyresponse to UV-C2
GO:0006979
IMP
Gene Ontologyresponse to oxidative stress1
GO:0009409
IMP
Gene Ontologyresponse to cold1
GO:0009845
IMP, IEP
Gene Ontologyseed germination1
GO:2000685
IMP
Gene Ontologypositive regulation of cellular response to X-ray1
GO:0002237
IMP
Gene Ontologyresponse to molecule of bacterial origin3
GO:0006303
IMP
Gene Ontologydouble-strand break repair via nonhomologous end joining3
GO:0015074
IMP
Gene OntologyDNA integration3
GO:1904975
IEP
Gene Ontologyresponse to bleomycin4
GO:0006273
IBA
Gene Ontologylagging strand elongation5
GO:0006266
IBA
Gene OntologyDNA ligation5

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0003910
IEA
GOA DatabaseDNA ligase (ATP) activity
GO:0003910
IBA
Gene OntologyDNA ligase (ATP) activity5
GO:0003910
IEA
InterProDNA ligase (ATP) activity
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0016874
IEA
GOA Databaseligase activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0003909
IEA
GOA DatabaseDNA ligase activity
GO:0003677
IEA
Gene OntologyDNA binding
GO:0003677
IEA
InterProDNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
ISM
Gene Ontologynucleus
GO:0005737
IBA
Gene Ontologycytoplasm5

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
IPR012310 DNA ligase, ATP-dependent, central
IPR000977 DNA ligase, ATP-dependent
IPR012340 Nucleic acid-binding, OB-fold
IPR012309 DNA ligase, ATP-dependent, C-terminal
IPR011084 DNA repair metallo-beta-lactamase
IPR012308 DNA ligase, ATP-dependent, N-terminal
IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily
Mapman id Description
14.4.5 DNA damage response.nonhomologous end-joining (NHEJ) repair.DNA ligase (LIG6)