Gene: AT1G66340
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G66340
- Transcript Identifier AT1G66340.1
- Gene Type Coding gene
- Location Chr1 : 24734698-24737366 : positive
Gene Family Information
- ID HOM05D000923
- #Genes/#Species 652/98
- Phylogenetic origin
- ID ORTHO05D000720
- #Genes/#Species 654/100
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G66340.1
- symbol ETR1
- Alias AtETR1,EIN1,ETHYLENE INSENSITIVE 1,ETR,ETHYLENE RESPONSE
- full_name ETHYLENE RESPONSE 1
- uniprot P49333
Descriptions
- Description Signal transduction histidine kinase, hybrid-type, ethylene sensor
- Computational description ETHYLENE RESPONSE 1 (ETR1); CONTAINS InterPro DOMAIN/s: Signal transduction histidine kinase, homodimeric (InterPro:IPR009082), Signal transduction histidine kinase, core (InterPro:IPR005467), Signal transduction histidine kinase, hybrid-type, ethylene sensor (InterPro:IPR014525), ATPase-like, ATP-binding domain (InterPro:IPR003594), CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789), Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain (InterPro:IPR003661), GAF (InterPro:IPR003018), Signal transduction histidine kinase-related protein, C-terminal (InterPro:IPR004358); BEST Arabidopsis thaliana protein match is: ethylene response sensor 1 (TAIR:AT2G40940.1); Has 102721 Blast hits to 98263 proteins in 3046 species: Archae - 757; Bacteria - 90102; Metazoa - 18; Fungi - 1611; Plants - 2314; Viruses - 21; Other Eukaryotes - 7898 (source: NCBI BLink).
- Loading (ortholog descriptions from ath)...
Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0000160 | IEA | GOA Database | phosphorelay signal transduction system | |
| GO:0000160 | IEA | InterPro | phosphorelay signal transduction system | |
| GO:0016310 | IEA | GOA Database | phosphorylation | |
| GO:0016310 | IEA | InterPro | phosphorylation | |
| GO:0009873 | IEA | GOA Database | ethylene-activated signaling pathway | |
| GO:0018106 | IEA | GOA Database | peptidyl-histidine phosphorylation | |
| GO:0006468 | IEA | GOA Database | protein phosphorylation | |
| GO:0009723 | IEA | GOA Database | response to ethylene | |
| GO:0009723 | IMP | Gene Ontology | response to ethylene | 1 |
| GO:0009723 | IEA | InterPro | response to ethylene | |
| GO:0007165 | IEA | GOA Database | signal transduction | |
| GO:0007165 | IEA | InterPro | signal transduction | |
| GO:0010182 | TAS | Gene Ontology | sugar mediated signaling pathway | 2 |
| GO:0009408 | IMP | Gene Ontology | response to heat | 3 |
| GO:0009737 | IMP | Gene Ontology | response to abscisic acid | 4 |
| GO:0009733 | IMP | Gene Ontology | response to auxin | 4 |
| GO:0009690 | IMP | Gene Ontology | cytokinin metabolic process | 4 |
| GO:0009651 | IEP | Gene Ontology | response to salt stress | 5 |
| GO:0009625 | IMP | Gene Ontology | response to insect | 6 |
| GO:0010162 | IMP | Gene Ontology | seed dormancy process | 7 |
| GO:0009739 | IMP | Gene Ontology | response to gibberellin | 7 |
| GO:0010105 | TAS | Gene Ontology | negative regulation of ethylene-activated signaling pathway | 8 |
| GO:0006952 | TAS | Gene Ontology | defense response | 9 |
| GO:0010119 | IMP | Gene Ontology | regulation of stomatal movement | 10 |
| GO:0050665 | IMP | Gene Ontology | hydrogen peroxide biosynthetic process | 10 |
| GO:0042742 | IMP | Gene Ontology | defense response to bacterium | 11 |
| GO:0052544 | IMP | Gene Ontology | defense response by callose deposition in cell wall | 11 |
| GO:0002237 | IMP | Gene Ontology | response to molecule of bacterial origin | 12 |
| GO:1900140 | IMP | Gene Ontology | regulation of seedling development | 1 |
| GO:0010087 | IMP | Gene Ontology | phloem or xylem histogenesis | 13 |
| GO:0051301 | IMP | Gene Ontology | cell division | 13 |
| GO:0009871 | TAS | Gene Ontology | jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway | 14 |
| GO:0009727 | IMP | Gene Ontology | detection of ethylene stimulus | 15 |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0016740 | IEA | GOA Database | transferase activity | |
| GO:0016301 | IEA | GOA Database | kinase activity | |
| GO:0005524 | IEA | GOA Database | ATP binding | |
| GO:0051740 | IEA | GOA Database | ethylene binding | |
| GO:0051740 | IDA IBA | Gene Ontology | ethylene binding | 16 17 |
| GO:0051740 | IEA | InterPro | ethylene binding | |
| GO:0000166 | IEA | GOA Database | nucleotide binding | |
| GO:0046872 | IEA | GOA Database | metal ion binding | |
| GO:0004673 | IEA | GOA Database | protein histidine kinase activity | |
| GO:0004673 | IMP ISS TAS | Gene Ontology | protein histidine kinase activity | 1 16 |
| GO:0005515 | IPI | Gene Ontology | protein binding | 18 |
| GO:0005515 | IEA | InterPro | protein binding | |
| GO:0016772 | IEA | GOA Database | transferase activity, transferring phosphorus-containing groups | |
| GO:0016772 | IEA | InterPro | transferase activity, transferring phosphorus-containing groups | |
| GO:0038199 | IEA | GOA Database | ethylene receptor activity | |
| GO:0038199 | IMP IBA | Gene Ontology | ethylene receptor activity | 17 19 |
| GO:0038199 | IEA | InterPro | ethylene receptor activity | |
| GO:0004672 | IEA | GOA Database | protein kinase activity | |
| GO:0004672 | IEA | InterPro | protein kinase activity | |
| GO:0000155 | IEA | Gene Ontology | phosphorelay sensor kinase activity | |
| GO:0000155 | IEA | InterPro | phosphorelay sensor kinase activity | |
| GO:0042802 | IPI | Gene Ontology | identical protein binding | 20 |
Cellular Component
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0005783 | IEA | GOA Database | endoplasmic reticulum | |
| GO:0005783 | IDA IBA | Gene Ontology | endoplasmic reticulum | 8 17 |
| GO:0016020 | IEA | GOA Database | membrane | |
| GO:0016021 | IEA | GOA Database | integral component of membrane | |
| GO:0005789 | IEA | GOA Database | endoplasmic reticulum membrane | |
| GO:0005789 | IDA | Gene Ontology | endoplasmic reticulum membrane | 8 |
| GO:0005789 | IEA | InterPro | endoplasmic reticulum membrane |
Color Legend
| Experimental Evidence |
| Computational Reviewed Evidence |
| Electronic Evidence |
| InterPro | Description |
|---|---|
| IPR036097 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily |
| IPR036890 | Histidine kinase/HSP90-like ATPase superfamily |
| IPR003018 | GAF domain |
| IPR003661 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain |
| IPR014525 | Ethylene receptor |
| IPR029016 | GAF-like domain superfamily |
| IPR001789 | Signal transduction response regulator, receiver domain |
| IPR003594 | Histidine kinase/HSP90-like ATPase |
| IPR011006 | CheY-like superfamily |
| IPR004358 | Signal transduction histidine kinase-related protein, C-terminal |
| Mapman id | Description |
|---|---|
| 11.5.2.1 | Phytohormone action.ethylene.perception and signal transduction.receptor protein (ETR/ERS) |