Gene: AT1G52500
General Information
Structural Information
- Species Arabidopsis thaliana
- Gene Identifier AT1G52500
- Transcript Identifier AT1G52500.2
- Gene Type Coding gene
- Location Chr1 : 19560043-19562855 : positive
Gene Family Information
- ID HOM05D006093
- #Genes/#Species 130/97
- Phylogenetic origin
- ID ORTHO05D007652
- #Genes/#Species 128/96
- Phylogenetic origin
Gene Duplication Information
Labels
Identifiers
- tid AT1G52500.2
- symbol MMH-1
- Alias ATFPG-1,A. THALIANA FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1,ATFPG-2,FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 2,ATMMH-1,MUTM homolog-1,ATMMH-2,FPG-1,FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 1,FPG-2,FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE 2,MMH-2,MMH,MUTM homolog
- uniprot O80358
Descriptions
- Description MUTM homolog-1
- Computational description MMH-2; CONTAINS InterPro DOMAIN/s: Ribosomal protein S13-like, H2TH (InterPro:IPR010979), DNA glycosylase/AP lyase, H2TH DNA-binding (InterPro:IPR015886), DNA glycosylase/AP lyase, catalytic domain (InterPro:IPR012319), DNA glycosylase/AP lyase (InterPro:IPR000191); Has 7507 Blast hits to 7502 proteins in 2073 species: Archae - 6; Bacteria - 4936; Metazoa - 104; Fungi - 102; Plants - 73; Viruses - 8; Other Eukaryotes - 2278 (source: NCBI BLink).
- Computational description MUTM homolog-1 (MMH-1); CONTAINS InterPro DOMAIN/s: Ribosomal protein S13-like, H2TH (InterPro:IPR010979), DNA glycosylase/AP lyase, H2TH DNA-binding (InterPro:IPR015886), DNA glycosylase/AP lyase, catalytic domain (InterPro:IPR012319), DNA glycosylase/AP lyase (InterPro:IPR000191); Has 11102 Blast hits to 10156 proteins in 2240 species: Archae - 10; Bacteria - 5065; Metazoa - 1812; Fungi - 570; Plants - 321; Viruses - 42; Other Eukaryotes - 3282 (source: NCBI BLink).
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Functional Annotation
Biological Process
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0008152 | IEA | GOA Database | metabolic process | |
| GO:0006284 | IBA IEA | Gene Ontology | base-excision repair | 1 |
| GO:0006284 | IEA | InterPro | base-excision repair | |
| GO:0006281 | IEA | GOA Database | DNA repair | |
| GO:0006281 | IDA | Gene Ontology | DNA repair | 2 |
| GO:0006281 | IEA | InterPro | DNA repair | |
| GO:0006979 | TAS | Gene Ontology | response to oxidative stress | 3 |
| GO:0006974 | IEA | GOA Database | cellular response to DNA damage stimulus |
Molecular Function
| GO term | Evidence(s) | Provider(s) | Description | Source(s) |
|---|---|---|---|---|
| GO:0003906 | IBA IEA | Gene Ontology | DNA-(apurinic or apyrimidinic site) endonuclease activity | 1 |
| GO:0003906 | IEA | InterPro | DNA-(apurinic or apyrimidinic site) endonuclease activity | |
| GO:0003824 | IEA | GOA Database | catalytic activity | |
| GO:0016829 | IEA | GOA Database | lyase activity | |
| GO:0003677 | IEA | GOA Database | DNA binding | |
| GO:0016798 | IEA | GOA Database | hydrolase activity, acting on glycosyl bonds | |
| GO:0016787 | IEA | GOA Database | hydrolase activity | |
| GO:0003676 | IEA | GOA Database | nucleic acid binding | |
| GO:0003676 | IEA | InterPro | nucleic acid binding | |
| GO:0016799 | IEA | GOA Database | hydrolase activity, hydrolyzing N-glycosyl compounds | |
| GO:0016799 | IEA | InterPro | hydrolase activity, hydrolyzing N-glycosyl compounds | |
| GO:0019104 | IEA | GOA Database | DNA N-glycosylase activity | |
| GO:0019104 | IDA ISS, IBA | Gene Ontology | DNA N-glycosylase activity | 1 2 3 |
| GO:0019104 | IEA | InterPro | DNA N-glycosylase activity | |
| GO:0008270 | IEA | Gene Ontology | zinc ion binding | |
| GO:0008270 | IEA | InterPro | zinc ion binding | |
| GO:0003684 | IEA | Gene Ontology | damaged DNA binding | |
| GO:0003684 | IEA | InterPro | damaged DNA binding | |
| GO:0008534 | IEA | Gene Ontology | oxidized purine nucleobase lesion DNA N-glycosylase activity | |
| GO:0008534 | IEA | InterPro | oxidized purine nucleob |