Gene: AT1G08130

General Information

Structural Information

  • Species Arabidopsis thaliana
  • Gene Identifier AT1G08130
  • Transcript Identifier AT1G08130.1
  • Gene Type Coding gene
  • Location Chr1 : 2542913-2547815 : negative

Gene Family Information

  • ID HOM05D001934
  • #Genes/#Species 342/100
  • Phylogenetic origin

Gene Duplication Information

Labels

Identifiers

  • tid AT1G08130.1
  • symbol LIG1
  • Alias ATLIG1,DNA ligase 1
  • uniprot Q42572

Descriptions

  • Description DNA ligase 1
  • Computational description DNA ligase 1 (LIG1); FUNCTIONS IN: DNA binding, DNA ligase (ATP) activity, ATP binding; INVOLVED IN: DNA repair, DNA replication, DNA recombination; LOCATED IN: mitochondrion, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA ligase, N-terminal (InterPro:IPR012308), ATP dependent DNA ligase, central (InterPro:IPR012310), ATP dependent DNA ligase, C-terminal (InterPro:IPR012309), ATP-dependent DNA ligase (InterPro:IPR000977), ATP-dependent DNA ligase, conserved site (InterPro:IPR016059); BEST Arabidopsis thaliana protein match is: ATP-dependent DNA ligase (TAIR:AT1G49250.1); Has 3556 Blast hits to 3521 proteins in 879 species: Archae - 298; Bacteria - 1538; Metazoa - 375; Fungi - 434; Plants - 112; Viruses - 159; Other Eukaryotes - 640 (source: NCBI BLink).
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Functional Annotation

Biological Process

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0051301
IEA
GOA Databasecell division
GO:0006260
IEA
GOA DatabaseDNA replication
GO:0006260
IMP
Gene OntologyDNA replication1
GO:0006281
IEA
GOA DatabaseDNA repair
GO:0006281
IEA
InterProDNA repair
GO:0006310
IEA
GOA DatabaseDNA recombination
GO:0006310
IEA
InterProDNA recombination
GO:0006974
IEA
GOA Databasecellular response to DNA damage stimulus
GO:0007049
IEA
GOA Databasecell cycle
GO:0071897
IEA
Gene OntologyDNA biosynthetic process
GO:0071897
IEA
InterProDNA biosynthetic process
GO:0080111
IMP
Gene OntologyDNA demethylation2
GO:0000012
IMP
Gene Ontologysingle strand break repair1
GO:0006302
IMP
Gene Ontologydouble-strand break repair1
GO:0006273
IBA
Gene Ontologylagging strand elongation3
GO:0006266
IBA
Gene OntologyDNA ligation3

Molecular Function

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0046872
IEA
GOA Databasemetal ion binding
GO:0016874
IEA
GOA Databaseligase activity
GO:0000166
IEA
GOA Databasenucleotide binding
GO:0003910
IEA
GOA DatabaseDNA ligase (ATP) activity
GO:0003910
IBA
Gene OntologyDNA ligase (ATP) activity3
GO:0003910
IEA
InterProDNA ligase (ATP) activity
GO:0005524
IEA
GOA DatabaseATP binding
GO:0005524
IEA
InterProATP binding
GO:0003909
IEA
GOA DatabaseDNA ligase activity
GO:0003677
IEA
Gene OntologyDNA binding
GO:0003677
IEA
InterProDNA binding

Cellular Component

GO termEvidence(s)Provider(s)DescriptionSource(s)
GO:0005634
IEA
GOA Databasenucleus
GO:0005634
IDA
ISM, IBA
Gene Ontologynucleus3 4
GO:0005739
IEA
GOA Databasemitochondrion
GO:0005739
IDA
IBA
Gene Ontologymitochondrion3 4
GO:0005730
IDA
Gene Ontologynucleolus2
GO:0005737
IBA
Gene Ontologycytoplasm3

Color Legend

Experimental Evidence
Computational Reviewed Evidence
Electronic Evidence
GO Sources: Primary Orthology Homology
Show redundant parents:
InterPro Description
IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily
IPR000977 DNA ligase, ATP-dependent
IPR012310 DNA ligase, ATP-dependent, central
IPR012340 Nucleic acid-binding, OB-fold
IPR012308 DNA ligase, ATP-dependent, N-terminal
IPR012309 DNA ligase, ATP-dependent, C-terminal
Mapman id Description
13.2.4.3 Cell cycle organisation.DNA replication.maturation.DNA ligase (LIG1)
14.5.5 DNA damage response.base excision repair (BER).DNA ligase (LIG1)