Child GO terms

Original GO term
GO:0010605
Description
negative regulation of macromolecule metabolic process
Type
BP

GO description genes species aly ath atr bra bvu cla cme cpa cre cru csi egr fve gma gra lja mdo mes mtr olu osa ppa ppe ptr rco sly stu tca tpa vvi zma
GO:0010629 negative regulation of gene expression 7492 31 261 660 177 336 208 194 194 182 64 243 210 209 222 435 328 153 338 257 272 57 208 182 210 301 206 251 249 206 237 210 232
GO:0010558 negative regulation of macromolecule biosynthetic process 5476 31 196 449 113 261 161 145 145 130 49 183 144 143 139 330 233 111 261 189 179 41 185 146 146 219 176 173 171 150 174 150 184
GO:2000113 negative regulation of cellular macromolecule biosynthetic process 5475 31 196 449 113 261 161 145 145 130 48 183 144 143 139 330 233 111 261 189 179 41 185 146 146 219 176 173 171 150 174 150 184
GO:0051253 negative regulation of RNA metabolic process 4709 31 178 428 98 234 121 122 122 113 40 165 128 129 123 285 205 99 216 160 160 33 125 123 128 179 129 155 150 129 158 130 144
GO:0045892 negative regulation of transcription, DNA-dependent 4708 31 178 428 98 234 121 122 122 113 39 165 128 129 123 285 205 99 216 160 160 33 125 123 128 179 129 155 150 129 158 130 144
GO:0016458 gene silencing 3945 31 111 483 100 138 121 94 94 89 36 107 114 113 127 217 158 86 163 127 159 29 111 100 110 150 104 136 132 105 110 106 115
GO:0031047 gene silencing by RNA 2964 31 76 400 81 95 93 64 69 66 25 78 84 81 97 162 118 64 117 99 115 20 88 71 78 113 79 103 102 78 80 81 87
GO:0016441 posttranscriptional gene silencing 2119 31 55 268 58 74 60 53 56 51 25 56 63 72 68 106 83 42 83 68 65 19 64 55 64 82 56 67 65 56 54 64 67
GO:0035194 posttranscriptional gene silencing by RNA 1891 31 49 260 53 63 55 43 48 46 20 52 57 58 60 96 72 37 72 62 56 16 59 49 54 72 52 59 57 49 48 57 60
GO:0045814 negative regulation of gene expression, epigenetic 1471 31 39 259 29 48 44 35 34 29 11 38 41 40 42 91 55 35 60 42 57 7 36 43 37 42 35 48 43 36 40 36 39
GO:0070918 production of small RNA involved in gene silencing by RNA 1445 31 39 150 43 47 44 33 38 33 13 39 44 45 52 81 51 35 57 46 49 9 49 36 43 55 39 52 59 36 36 43 49
GO:0006342 chromatin silencing 1349 31 34 254 26 44 40 30 29 26 10 34 37 37 37 81 51 32 54 37 54 6 33 41 34 36 32 45 40 33 36 32 34
GO:0016246 RNA interference 1208 31 32 187 34 37 32 27 30 31 11 32 35 37 39 56 44 26 42 36 33 7 43 31 35 42 31 41 38 31 32 35 41
GO:0030422 production of siRNA involved in RNA interference 1082 31 29 143 32 35 31 26 29 26 9 29 34 35 37 54 37 24 42 30 30 6 41 27 33 39 28 34 35 26 29 33 39
GO:0035195 gene silencing by miRNA 1074 31 26 201 29 35 32 22 28 24 9 29 30 32 30 54 38 19 39 34 28 7 32 29 27 40 27 29 30 25 25 28 36
GO:0051248 negative regulation of protein metabolic process 911 31 28 67 17 49 42 25 25 20 7 27 19 17 19 43 36 15 43 30 19 7 70 22 19 40 49 16 21 24 28 18 49
GO:0032269 negative regulation of cellular protein metabolic process 904 31 28 66 17 45 42 25 25 20 7 26 19 17 19 43 36 15 43 30 19 7 70 22 19 40 49 16 21 24 27 18 49
GO:0035196 production of miRNAs involved in gene silencing by miRNA 770 31 19 136 23 24 21 16 22 17 7 21 20 24 23 40 24 16 26 22 21 5 26 15 19 31 20 24 24 16 17 21 30
GO:0010267 production of ta-siRNAs involved in RNA interference 640 31 15 111 21 17 18 15 16 14 6 16 20 20 21 33 22 13 23 15 16 3 25 11 18 25 15 20 21 14 14 19 23
GO:0051053 negative regulation of DNA metabolic process 488 31 16 18 13 18 14 15 15 12 9 15 14 12 13 29 17 9 23 18 17 9 14 13 16 23 15 19 21 14 15 17 15
GO:0031048 chromatin silencing by small RNA 471 30 10 119 11 11 14 7 8 8 4 9 11 11 13 28 15 14 20 14 19 0 11 14 9 10 8 17 17 10 10 9 10
GO:0031400 negative regulation of protein modification process 465 31 21 54 10 31 11 10 12 12 4 18 12 11 12 21 20 8 19 14 12 5 18 8 10 16 11 10 13 12 21 10 19
GO:0017148 negative regulation of translation 439 31 7 12 7 14 31 15 13 8 3 8 7 6 7 22 16 7 24 16 7 2 52 14 9 24 38 6 8 12 6 8 30
GO:0006346 methylation-dependent chromatin silencing 405 31 10 124 6 15 7 9 10 7 3 11 7 13 9 13 17 7 13 10 12 2 6 8 8 8 8 14 9 10 12 8 9
GO:0008156 negative regulation of DNA replication 357 31 12 11 9 14 10 9 11 10 6 11 10 8 10 24 13 6 22 14 13 6 9 10 10 17 10 13 14 10 11 13 11
GO:0060968 regulation of gene silencing 355 31 13 21 7 12 14 13 10 9 3 12 13 14 13 19 16 4 18 12 13 2 9 11 16 13 11 9 9 11 11 8 9
GO:0080188 RNA-directed DNA methylation 350 31 13 12 10 13 13 8 9 7 3 11 9 9 11 30 12 10 13 11 22 4 11 13 9 10 8 15 14 10 11 10 9
GO:2000104 negative regulation of DNA-dependent DNA replication 318 31 10 9 8 12 9 8 10 9 5 9 9 7 9 20 12 6 21 13 11 5 8 10 9 15 9 12 13 9 9 12 10
GO:0001933 negative regulation of protein phosphorylation 293 31 14 48 6 24 5 6 7 7 3 12 7 6 7 10 13 4 11 8 6 4 11 4 6 8 6 6 8 6 14 6 10
GO:0006469 negative regulation of protein kinase activity 260 31 13 47 5 23 4 5 6 6 2 11 6 5 6 8 12 4 9 7 5 2 10 3 5 7 5 5 7 5 13 5 9
GO:0071901 negative regulation of protein serine/threonine kinase activity 218 31 9 42 5 13 4 5 6 5 2 9 6 5 5 8 10 4 6 7 5 2 5 2 4 7 5 5 7 5 9 5 6
GO:0032876 negative regulation of DNA endoreduplication 210 31 6 6 6 7 7 6 8 6 3 6 6 5 6 10 8 4 10 9 7 3 6 9 6 10 6 9 9 6 6 6 8
GO:0031935 regulation of chromatin silencing 199 31 9 14 4 7 7 7 5 5 2 9 5 6 6 11 9 3 7 7 7 2 5 6 6 6 7 6 5 7 8 5 6
GO:0031053 primary miRNA processing 186 31 6 6 5 7 6 3 5 5 4 7 5 4 4 9 10 5 7 9 7 3 6 7 5 10 6 5 6 5 4 7 8
GO:0010599 production of lsiRNA involved in RNA interference 171 30 3 4 9 3 6 5 6 3 2 4 6 5 6 15 4 4 7 2 4 0 11 2 6 8 6 9 8 3 3 6 11
GO:0070919 production of siRNA involved in chromatin silencing by small RNA 161 30 5 3 6 4 6 2 3 3 1 4 5 5 7 16 7 5 9 6 11 0 4 5 4 4 2 9 9 5 3 4 4
GO:0060147 regulation of posttranscriptional gene silencing 154 30 4 5 3 5 7 6 5 4 1 3 8 8 7 8 7 1 11 5 6 0 4 5 10 7 4 3 4 4 3 3 3
GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 136 28 7 27 3 10 2 3 4 3 0 7 4 3 4 5 6 2 4 4 3 0 2 0 2 5 3 3 4 3 7 3 3
GO:0045910 negative regulation of DNA recombination 132 31 4 7 4 4 4 6 4 2 3 4 4 4 3 5 4 3 1 4 4 3 5 3 6 6 5 6 7 4 4 4 5
GO:0060966 regulation of gene silencing by RNA 119 30 2 5 3 5 7 3 3 3 1 3 7 4 4 8 4 1 7 5 3 0 4 5 5 4 5 3 3 3 3 3 3
GO:0010495 long-distance posttranscriptional gene silencing 119 30 4 4 3 5 3 3 4 3 2 3 3 4 4 6 5 4 8 4 4 0 4 6 3 3 3 5 5 3 4 3 4
GO:0035279 mRNA cleavage involved in gene silencing by miRNA 113 30 4 7 3 6 3 3 4 4 1 4 3 5 3 5 4 4 3 4 3 0 5 3 3 5 3 3 3 3 4 3 5
GO:1901984 negative regulation of protein acetylation 102 31 4 3 3 4 3 3 3 3 1 3 3 3 2 7 5 3 5 4 3 1 4 3 2 5 3 3 3 3 4 2 4
GO:2000757 negative regulation of peptidyl-lysine acetylation 102 31 4 3 3 4 3 3 3 3 1 3 3 3 2 7 5 3 5 4 3 1 4 3 2 5 3 3 3 3 4 2 4
GO:0035067 negative regulation of histone acetylation 102 31 4 3 3 4 3 3 3 3 1 3 3 3 2 7 5 3 5 4 3 1 4 3 2 5 3 3 3 3 4 2 4
GO:0031057 negative regulation of histone modification 102 31 4 3 3 4 3 3 3 3 1 3 3 3 2 7 5 3 5 4 3 1 4 3 2 5 3 3 3 3 4 2 4
GO:0060964 regulation of gene silencing by miRNA 88 29 2 4 2 4 6 2 2 2 1 2 6 3 3 6 3 0 5 4 2 0 3 4 4 3 3 2 2 2 2 2 2
GO:0043407 negative regulation of MAP kinase activity 82 31 2 15 2 3 2 2 2 2 2 2 2 2 1 3 4 2 2 3 2 2 3 2 2 2 2 2 3 2 2 2 3
GO:0006344 maintenance of chromatin silencing 81 30 2 2 2 3 2 4 2 2 0 2 4 2 2 6 3 3 1 3 5 1 2 1 3 5 3 2 3 3 3 3 2
GO:0090308 regulation of methylation-dependent chromatin silencing 68 30 5 6 1 3 1 3 2 2 1 5 1 1 2 3 4 1 1 2 3 0 1 2 1 2 2 1 1 3 5 1 2
GO:0031937 positive regulation of chromatin silencing 68 30 5 6 1 3 1 3 2 2 1 5 1 1 2 3 4 1 1 2 3 0 1 2 1 2 2 1 1 3 5 1 2
GO:0090309 positive regulation of methylation-dependent chromatin silencing 68 30 5 6 1 3 1 3 2 2 1 5 1 1 2 3 4 1 1 2 3 0 1 2 1 2 2 1 1 3 5 1 2
GO:0060148 positive regulation of posttranscriptional gene silencing 66 29 2 1 1 1 1 4 3 2 0 1 2 5 4 2 4 1 6 1 4 0 1 1 6 4 1 1 2 2 1 1 1
GO:0045128 negative regulation of reciprocal meiotic recombination 62 30 2 2 2 2 2 3 2 1 2 2 2 2 1 2 2 1 0 2 2 2 2 2 3 3 2 3 3 2 2 2 2
GO:0042177 negative regulation of protein catabolic process 55 28 2 3 1 6 2 1 1 2 0 3 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 3 1 4
GO:0033562 co-transcriptional gene silencing by RNA interference machinery 53 27 1 1 1 1 2 1 2 1 0 1 2 2 2 4 4 2 4 2 2 0 0 1 2 2 2 3 3 2 1 2 0
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0051444 negative regulation of ubiquitin-protein ligase activity 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0031397 negative regulation of protein ubiquitination 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:1901799 negative regulation of proteasomal protein catabolic process 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0045900 negative regulation of translational elongation 48 30 1 1 1 2 2 1 1 2 1 1 1 1 1 5 2 1 4 1 1 0 1 3 1 2 3 1 1 1 1 1 3
GO:0060564 negative regulation of mitotic anaphase-promoting complex activity 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0045861 negative regulation of proteolysis 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 48 28 2 2 1 2 2 1 1 2 0 2 1 1 3 3 1 1 2 2 2 0 2 0 1 2 1 1 1 2 2 1 4
GO:0045014 negative regulation of transcription by glucose 48 29 1 1 1 2 1 1 1 1 0 1 1 1 1 4 4 2 2 2 1 0 1 4 1 2 1 3 3 1 1 2 1
GO:0045013 carbon catabolite repression of transcription 48 29 1 1 1 2 1 1 1 1 0 1 1 1 1 4 4 2 2 2 1 0 1 4 1 2 1 3 3 1 1 2 1
GO:0035278 negative regulation of translation involved in gene silencing by miRNA 45 27 1 2 1 2 2 0 1 1 0 2 1 1 1 2 3 1 1 4 1 0 1 2 1 4 2 1 2 1 0 2 2
GO:0040033 negative regulation of translation, ncRNA-mediated 45 27 1 2 1 2 2 0 1 1 0 2 1 1 1 2 3 1 1 4 1 0 1 2 1 4 2 1 2 1 0 2 2
GO:0016480 negative regulation of transcription from RNA polymerase III promoter 39 30 1 1 1 1 1 1 1 1 1 1 1 1 1 2 5 0 2 1 1 1 1 2 1 1 3 1 1 1 1 1 1
GO:0032205 negative regulation of telomere maintenance 39 29 2 2 1 2 1 1 1 1 1 2 1 1 1 4 1 0 1 1 2 1 1 0 1 2 1 1 1 1 2 1 1
GO:0032211 negative regulation of telomere maintenance via telomerase 39 29 2 2 1 2 1 1 1 1 1 2 1 1 1 4 1 0 1 1 2 1 1 0 1 2 1 1 1 1 2 1 1
GO:0035281 pre-miRNA export from nucleus 36 30 1 1 1 1 1 1 1 1 1 2 1 1 1 2 2 1 2 1 1 1 1 2 1 1 1 0 1 1 2 1 1
GO:0006348 chromatin silencing at telomere 36 29 1 1 1 2 1 1 1 1 1 1 1 1 1 2 1 0 3 1 1 1 1 1 1 1 1 1 0 1 1 2 3
GO:0031054 pre-miRNA processing 35 27 1 1 1 2 1 1 1 2 0 1 1 2 1 2 2 1 0 1 1 0 3 1 1 2 1 1 1 1 1 1 0
GO:0070922 small RNA loading onto RISC 33 25 1 1 1 3 1 1 1 1 0 1 1 1 1 2 3 0 2 2 1 0 0 0 1 2 1 1 1 1 1 1 0
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 33 30 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 0 2 1 1 2 1 1 1 1 1 1 1 1 1 1 1
GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA 33 25 1 1 1 3 1 1 1 1 0 1 1 1 1 2 3 0 2 2 1 0 0 0 1 2 1 1 1 1 1 1 0
GO:0048478 replication fork protection 31 29 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 0 1 1 0 1 1 1 1 1 1 1 1 1
GO:0010964 regulation of chromatin silencing by small RNA 31 28 0 1 1 1 1 1 1 1 0 1 1 1 1 2 1 1 2 1 1 0 1 1 1 1 2 1 1 1 1 1 1
GO:0090241 negative regulation of histone H4 acetylation 28 28 1 1 1 1 1 1 1 1 0 1 1 1 0 1 1 1 0 1 1 1 1 1 1 1 1 1 1 1 1 1 1
GO:0032055 negative regulation of translation in response to stress 27 26 1 1 1 2 1 1 1 1 0 1 1 1 1 1 0 1 1 1 1 0 1 0 1 1 1 0 1 1 1 1 1
GO:0080149 sucrose induced translational repression 27 26 1 1 1 2 1 1 1 1 0 1 1 1 1 1 0 1 1 1 1 0 1 0 1 1 1 0 1 1 1 1 1
GO:0060145 viral gene silencing in virus induced gene silencing 23 23 1 1 1 1 1 0 1 1 0 1 1 1 1 1 1 0 1 1 1 0 0 0 1 1 0 1 1 1 1 1 0
GO:0033234 negative regulation of protein sumoylation 22 22 1 1 0 1 1 0 1 0 0 1 1 1 0 1 1 0 1 0 1 0 1 1 1 1 1 0 1 1 1 1 1
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 19 15 0 0 0 0 0 1 1 0 0 1 1 0 1 0 0 0 1 0 1 0 1 0 1 1 0 2 2 0 1 1 3
GO:0031936 negative regulation of chromatin silencing 9 7 0 2 0 0 0 0 0 0 0 0 0 1 0 2 1 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0
GO:0060969 negative regulation of gene silencing 9 7 0 2 0 0 0 0 0 0 0 0 0 1 0 2 1 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0
GO:0000188 inactivation of MAPK activity 3 1 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
GO:0045947 negative regulation of translational initiation 2 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
GO:0000183 chromatin silencing at rDNA 2 2 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
GO:0030466 chromatin silencing at silent mating-type cassette 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
GO:0032785 negative regulation of DNA-dependent transcription, elongation 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0