Module
- Number
- 94
- Regulatory Genes
- 7
- Module Genes
- 24
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
lin-54 | JC8.6 | WBGene00003037 | 425 | View | |
ztf-25 | Y6G8.3 | WBGene00012405 | 334 | View | |
D2030.7 | D2030.7 | WBGene00008417 | 327 | View | |
dnj-11 | F38A5.13 | WBGene00001029 | 175 |
This gene encodes a protein containing a DnaJ ('J') domain.
|
View |
nhr-63 | C06C6.4 | WBGene00003653 | 116 | View | |
nfyc-1 | F23F1.1 | WBGene00017742 | 111 | View | |
elt-2 | C33D3.1 | WBGene00001250 | 102 |
elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
|
View |
CLR Predictions
23 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
C24D10.5 | C24D10.5 | WBGene00016056 | View | |
C28A5.2 | C28A5.2 | WBGene00007789 | View | |
C37A5.7 | C37A5.7 | WBGene00007991 | View | |
C54G6.1 | C54G6.1 | WBGene00016930 | View | |
D1037.1 | D1037.1 | WBGene00017025 | View | |
ekl-5 | Y26E6A.1 | WBGene00012512 | View | |
F23D12.2 | F23D12.2 | WBGene00009086 |
This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
|
View |
F31B9.3 | F31B9.3 | WBGene00009280 | View | |
F59D12.5 | F59D12.5 | WBGene00010332 | View | |
H04D03.2 | H04D03.2 | WBGene00010363 | View | |
K09E3.7 | K09E3.7 | WBGene00019578 | View | |
M03C11.6 | M03C11.6 | WBGene00010843 | View | |
mdt-17 | Y113G7B.18 | WBGene00007017 | View | |
polq-1 | W03A3.2 | WBGene00020964 |
polq-1 encodes a protein, containing an amino-terminal DEAD/DEAH box helicase domain and a carboxy-terminal DNA polymerase I-like domain, that is most closely related to vertebrate DNA polymerase theta (POLQ) and Drosophila Mus308; in C. elegans, polq-1 functions in a novel and brc-1-dependent pathway to repair DNA interstrand cross-links (ICLs) and thus confer resistance to DNA-damaging agents.
|
View |
ppfr-4 | Y71H2B.3 | WBGene00022193 |
ppfr-4 encodes the C. elegans ortholog of TAP42, a protein phosphatase 2A (PP2A) regulatory subunit; ppfr-4(RNAi) in wild-type animals results in fertility defects in F1 hermaphrodites, who exhibit a 90-95% decrease in the total number of eggs laid.
|
View |
pqn-82 | Y39A3CR.7 | WBGene00004163 |
The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
|
View |
T07C12.12 | T07C12.12 | WBGene00011576 | View | |
T23G11.7 | T23G11.7 | WBGene00011972 | View | |
T23G4.3 | T23G4.3 | WBGene00011959 | View | |
W02D9.4 | W02D9.4 | WBGene00012210 | View | |
Y105E8A.8 | Y105E8A.8 | WBGene00013669 | View | |
Y116A8C.13 | Y116A8C.13 | WBGene00013792 | View | |
Y45F3A.9 | Y45F3A.9 | WBGene00012864 | View | |
Y48G9A.11 | Y48G9A.11 | WBGene00021704 | View |