Module
- Number
- 40
- Regulatory Genes
- 5
- Module Genes
- 26
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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tbx-34 | Y47D3A.10 | WBGene00006553 | 831 |
tbx-34 encodes a diverged member of the T-box transcription factor family; by homology, TBX-34 is predicted to function as a transcriptional regulator during development, but as loss of tbx-34 activity via RNAi results in no obvious defects, the precise role of TBX-34 in C. elegans development and/or behavior is not yet known.
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Y52B11A.9 | Y52B11A.9 | WBGene00013128 | 249 | View | |
bed-2 | Y47D3B.9 | WBGene00012943 | 175 | View | |
skn-1 | T19E7.2 | WBGene00004804 | 166 |
skn-1 encodes a transcription factor with similarity to the basic region of bZip transcription factors; during early embryogenesis, maternally provided SKN-1 is required for specification of the EMS blastomere, a mesendodermal precursor that gives rise to pharyngeal, muscle, and intestinal cells; later, during postembryonic development, SKN-1 functions in the p38 MAPK pathway to regulate the oxidative stress response and in parallel to DAF-16/FOXO in the DAF-2-mediated insulin/IGF-1-like signaling pathway to regulate adult lifespan; in vitro assays indicate that SKN-1 can be directly phosphorylated by the AKT-1, AKT-2, and SGK-1 kinases that lie downstream of DAF-2 in the insulin signaling pathway and in vivo experiments suggest that this phosphorylation is essential for regulation of SKN-1 nuclear accumulation and hence, transcriptional regulator activity; in the early embryo, SKN-1 is detected at highest levels in nuclei of the P1 blastomere and its descendants through the 8-cell stage of embryogenesis; later in embryogenesis, SKN-1 is observed in all hypodermal and intestinal nuclei, with reporter constructs indicating that intestinal expression begins as early as the 50-100-cell stage; in larvae and young adults, SKN-1::GFP reporters are expressed in the intestine and ASI neurons, with expression in intestinal nuclei enhanced under conditions of stress or reduced DAF-2 signaling.
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F45C12.2 | F45C12.2 | WBGene00018433 | 103 | View |
CLR Predictions
16 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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B0205.10 | B0205.10 | WBGene00015024 | View | |
C06A8.6 | C06A8.6 | WBGene00015516 | View | |
C09B9.2 | C09B9.2 | WBGene00015627 | View | |
C10H11.7 | C10H11.7 | WBGene00015696 | View | |
C15H7.3 | C15H7.3 | WBGene00007610 | View | |
C16C8.18 | C16C8.18 | WBGene00015855 | View | |
C38C3.3 | C38C3.3 | WBGene00016512 | View | |
C43G2.3 | C43G2.3 | WBGene00016612 | View | |
F29B9.7 | F29B9.7 | WBGene00017922 | View | |
F31E8.5 | F31E8.5 | WBGene00017955 | View | |
F36A2.11 | F36A2.11 | WBGene00009458 | View | |
F36A4.2 | F36A4.2 | WBGene00018081 | View | |
F36A4.4 | F36A4.4 | WBGene00018083 | View | |
F40G12.10 | F40G12.10 | WBGene00009605 | View | |
F47D12.7 | F47D12.7 | WBGene00018563 | View | |
K04G2.4 | K04G2.4 | WBGene00010563 | View | |
K08C9.1 | K08C9.1 | WBGene00010650 | View | |
R09E10.3 | R09E10.3 | WBGene00011173 | View | |
T22C1.9 | T22C1.9 | WBGene00011919 | View | |
tbx-34 | Y47D3A.10 | WBGene00006553 |
tbx-34 encodes a diverged member of the T-box transcription factor family; by homology, TBX-34 is predicted to function as a transcriptional regulator during development, but as loss of tbx-34 activity via RNAi results in no obvious defects, the precise role of TBX-34 in C. elegans development and/or behavior is not yet known.
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Y113G7C.1 | Y113G7C.1 | WBGene00013771 | View | |
Y37D8A.8 | Y37D8A.8 | WBGene00012549 | View | |
Y43F8C.5 | Y43F8C.5 | WBGene00012827 | View | |
ZK1248.5 | ZK1248.5 | WBGene00022876 | View | |
ZK418.2 | ZK418.2 | WBGene00022732 | View | |
ZK858.2 | ZK858.2 | WBGene00014116 | View |