Module
- Number
- 282
- Regulatory Genes
- 3
- Module Genes
- 4
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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nhr-55 | T01G6.7 | WBGene00003645 | 256 |
nhr-55 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
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nhr-8 | F33D4.1 | WBGene00003607 | 224 |
The nhr-8 gene encodes a nuclear hormone receptor homolog; nhr-8(ok186) mutants have abnormally low resistance to the toxins colchicine and chloroquine.
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zip-5 | C34D1.5 | WBGene00007932 | 200 |
zip-5 encodes a bZip transcription factor; a zip-5::gfp promoter reporter gene fusion is expressed primarily in the nervous system, with mid- and late-stage embryos showing strong expression in head neurons, while larvae show expression in the ventral nerve cord and head and tail neurons; adults also show GFP expression in head muscles and intermittently in the intestine.
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CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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B0024.4 | B0024.4 | WBGene00007097 | View | |
C50F4.9 | C50F4.9 | WBGene00008234 | View | |
F44G3.10 | F44G3.10 | WBGene00009710 |
F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
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lys-3 | Y22F5A.6 | WBGene00003092 |
lys-3 encodes one of a family of ten C. elegans lysozyme genes that are homologous to lysozymes in the amoeboid protozoon Entamoeba histolytica.
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