Module
- Number
- 247
- Regulatory Genes
- 4
- Module Genes
- 5
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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peb-1 | T14F9.4 | WBGene00003968 | 625 |
peb-1 encodes a novel DNA-binding protein; during development, peb-1 activity is required for proper morphogenesis of the pharynx, vulva, and hindgut and for normal molting, feeding, and body morphology; in vitro, PEB-1 exhibits sequence-specific DNA binding to a regulatory sequence known as subelement C, which directs pharynx-specific myo-2 expression and in yeast, PEB-1 exhibits modest transcription activation activity; PEB-1 is expressed in the nuclei of all pharyngeal cells (except neurons) from the comma stage of embryogenesis through late larval stages; in addition, PEB-1 is expressed dynamically in non-pharyngeal cells, including the vulva, germline, hindgut, and hypodermis.
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Y62E10A.17 | Y62E10A.17 | WBGene00013383 | 216 | View | |
rab-6.2 | T25G12.4 | WBGene00004270 | 111 |
rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction.
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unc-44 | B0350.2 | WBGene00006780 | 107 |
The unc-44 gene encodes an ankyrin-like protein required for proper sex myoblast and axonal guidance during development.
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CLR Predictions
6 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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C14F11.6 | C14F11.6 | WBGene00015781 | View | |
F14B8.5 | F14B8.5 | WBGene00017447 | View | |
mlt-11 | W01F3.3 | WBGene00012186 | View | |
pat-2 | F54F2.1 | WBGene00003929 |
pat-2 encodes an alpha integrin subunit; during embryogenesis, pat-2 is essential for body wall muscle assembly and function and hence, proper elongation and hatching.
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set-30 | ZC8.3 | WBGene00022499 |
set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes.
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