Module
- Number
- 230
- Regulatory Genes
- 4
- Module Genes
- 5
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
Y43C5A.2 | Y43C5A.2 | WBGene00012782 | 478 | View | |
ceh-21 | T26C11.6 | WBGene00000444 | 248 |
ceh-21 encodes a a ONECUT class CUT homeobox protein with a single N-terminal cut domain and an OCAM domain; the cut domain may be a compact DNA-binding domain composed of alpha helices; the OCAM domain is a nematode-specific motif conserved between CEH-21, CEH-41, and T02B5.2; ceh-21 is one of three nematode-specific ONECUT genes in a cluster with ceh-39 and ceh-41; CEH-21 may be required for muscle formation and differentiation, and is expressed in muscle precursor cells and differentiated gut cells; ceh-21 has no obvious function in mass RNAi assays.
|
View |
ras-1 | C44C11.1 | WBGene00004310 | 203 |
ras-1 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:21928) (RRAS2; OMIM:600098), which when mutated leads to disease.
|
View |
ZK1320.3 | ZK1320.3 | WBGene00014253 | 126 | View |
CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
M02D8.1 | M02D8.1 | WBGene00019727 | View | |
mup-2 | T22E5.5 | WBGene00003495 |
mup-2 encodes the muscle contractile protein troponin T ( TnT ) homologous to vertebrate and invertebrate TnT and contains an invertebrate- specific COOH -terminal tail; mup-2 affects embryonic body wall muscle cell contraction, sarcomere organization, cell positioning, regulated muscle contraction in larval and adult body wall muscle, epidermal morphogenesis, and is required for proper function of the hermaphrodite nonstriated oviduct myoepithelial sheath, proper growth, and fertility.
|
View |
npa-1 | VC5.3 | WBGene00003786 |
npa-1 encodes a large polyprotein precursor that is posttranslationally cleaved to multiple units of ~14.5kDa, each of which is a strong binding protein for fatty acids and retinol (Vitamin A); the lipid binding sites of NPA-1-derived peptides are unusually apolar; NPA-1-derived peptides probably are carrier proteins that enable distribution of these lipids within nematodes; NPA-1-derived peptides are also secreted by parasitic nematode species.
|
View |
ost-1 | C44B12.2 | WBGene00003893 |
ost-1 encodes the C. elegans ortholog of the conserved basement membrane glycoprotein component osteonectin/SPARC/BM-40; loss of ost-1 function via RNAi indicates that ost-1 activity is required for embryonic and larval development, as well as for normal gut development, body size, and fecundity; an OST-1::GFP reporter fusion protein localizes to the basement membranes along body wall and sex muscles, as well as around the pharynx and gonad, with particular concentration at the spermatheca and distal tip cells.
|
View |
ttr-41 | F10G7.11 | WBGene00017374 | View |