Module
- Number
- 221
- Regulatory Genes
- 5
- Module Genes
- 5
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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nhr-258 | C26B2.4 | WBGene00016126 | 286 | View | |
ZK673.4 | ZK673.4 | WBGene00014060 | 243 |
ZK673.4 encodes a protein with a THAP or THAP-like domain; other proteins with such domains include LIN-15A, LIN-15B, LIN-36, and HIM-17 (which all interact with LIN-35/Rb), as well as CDC-14B, CTB-1, GON-14, and ~100 other proteins such as Drosophila P element transposase and human nuclear proapoptotic factor THAP1.
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aha-1 | C25A1.11 | WBGene00000095 | 226 |
aha-1 encodes an ortholog of human aryl-hydrocarbon receptor nuclear translocator; interacts with AHR-1 and HIF-1 in vitro, requires HIF-1 for proper localization, and is expressed ubiquitously.
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zfp-3 | W05H7.4 | WBGene00021047 | 199 | View | |
ceh-2 | C27A12.5 | WBGene00000429 | 132 |
ceh-2 encodes a homeodomain protein homologous to Drosophila empty spiracles (EMS) and the vertebrate EMX1 and EMX2 proteins (OMIM:600034, 600035); although the exact biological role of CEH-2 in C. elegans development and/or behavior is not yet known, expression in pharyngeal neurons and muscle, as well as vulval cells (vulB1, vulB2, and vulC) at late stages of development suggests that CEH-2 may play a role in terminal differentiation events in diverse cell types.
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CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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bli-2 | F59E12.12 | WBGene00000252 |
A cuticle collagen involved in strut assembly in the adult cuticle.
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col-38 | F54C9.4 | WBGene00000615 |
col-38 encodes a member of the collagen superfamily containing collagen triple helix repeats (20 copies) required for normal body morphology.
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col-71 | Y49F6B.10 | WBGene00000647 | View | |
rol-1 | Y57A10A.11 | WBGene00004394 |
rol-1 encodes a nematode cuticular collagen required for normal body morphology at the adult stage of development; rol-1 expression is under the control of the heterochronic pathway, as heterochronic mutants that synthesize adult cuticle early produce animals that roll as larvae, while heterochronic mutants that fail to execute normal adult development never display the roller phenotype.
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Y51H7C.13 | Y51H7C.13 | WBGene00021791 | View |