Module
- Number
- 19
- Regulatory Genes
- 4
- Module Genes
- 36
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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T22E7.2 | T22E7.2 | WBGene00020694 | 689 | View | |
nhr-167 | C49F5.4 | WBGene00008208 | 377 | View | |
C34D1.1 | C34D1.1 | WBGene00007929 | 248 | View | |
C01F4.2 | C01F4.2 | WBGene00015303 | 119 | View |
CLR Predictions
5 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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abch-1 | C56E6.5 | WBGene00016973 | View | |
B0507.6 | B0507.6 | WBGene00015223 | View | |
C03F11.1 | C03F11.1 | WBGene00015387 | View | |
C18H7.6 | C18H7.6 | WBGene00015996 | View | |
C36B7.3 | C36B7.3 | WBGene00016466 | View | |
C56A3.3 | C56A3.3 | WBGene00008342 |
C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
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che-2 | F38G1.1 | WBGene00000484 |
che-2 encodes a protein that contains G-protein beta-like WD-40 repeats that affects chemotaxis, dauer formation, and longevity; expressed in the cilia of most ciliated sensory neurons, some head neurons, and male tail rays.
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cyp-33B1 | C25E10.2 | WBGene00016092 | View | |
dct-15 | W08D2.3 | WBGene00012340 | View | |
dgk-3 | F54G8.2 | WBGene00000960 |
dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
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eak-4 | F53B2.3 | WBGene00009955 |
eak-4 encodes a novel protein that contains an N-myristoylation signal; eak-4 acts in parallel to akt-1 to regulate insulin-like signaling and dauer formation; EAK-4 is expressed primarily in the neuroendocrine XXXL/R cells, where it associates with the plasma membrane.
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F40F11.4 | F40F11.4 | WBGene00009589 | View | |
F47G4.5 | F47G4.5 | WBGene00009826 |
F47G4.5 encodes a paralog of MEI-2 that, like MEI-2, binds MEI-1 in vitro; F47G4.5 might thus be an alternative ligand of MEI-1 in vivo.
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F59A1.11 | F59A1.11 | WBGene00010297 | View | |
F59A3.7 | F59A3.7 | WBGene00019080 | View | |
fbxa-199 | T06E6.3 | WBGene00005931 |
srx-40 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
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gbb-1 | Y41G9A.4 | WBGene00021528 |
Y41G9A.4 ('gbb-1') encodes, by alternative splicing, one isoform of a subunit of the GABAB receptor dimer (Y41G9A.4/ZK180.1, or 'GBB-1/2') that is required for inhibition of cholinergic motor neurons by GABA, and thus for normally restrained movement and aldicarb resistance; Y41G9A.4/gbb-1(tm1406) mutants move abnormally fast, with abnormally few changes of direction; Y41G9A.4 is orthologous to human GABBR1 (OMIM:603540).
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hlh-34 | T01D3.2 | WBGene00011327 | View | |
ncx-5 | Y32F6B.2 | WBGene00003570 |
ncx-5 encodes a putative 4Na[+]/1Ca[2+],1K[+] exchanger, orthologous to human SLC24A1-5 and paralogous to NCX-4; NCX-5 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-5 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-5 has no obvious function in mass RNAi assays.
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nhr-208 | R07B7.15 | WBGene00011099 | View | |
nmr-1 | F07F6.6 | WBGene00003774 |
nmr-1 encodes an NMDA-type ionotropic glutamate receptor subunit that affects the duration of forward movement which is important during foraging behavior, and also affects osmotic avoidance; the slow kinetics typical of NMDA-dependent currents are likely important for its effect on forward movement.
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R04A9.1 | R04A9.1 | WBGene00019861 | View | |
R13H7.2 | R13H7.2 | WBGene00020069 | View | |
srh-44 | B0334.7 | WBGene00005267 | View | |
srj-4 | C27A7.7 | WBGene00005592 | View | |
srsx-17 | F58D7.1 | WBGene00019032 | View | |
srw-1 | Y75B12B.7 | WBGene00005748 | View | |
srw-61 | H25K10.7 | WBGene00005808 | View | |
T01G6.1 | T01G6.1 | WBGene00020151 | View | |
T10E9.5 | T10E9.5 | WBGene00020415 | View | |
T14B1.2 | T14B1.2 | WBGene00011764 | View | |
Y110A7A.2 | Y110A7A.2 | WBGene00022454 | View | |
Y116A8B.5 | Y116A8B.5 | WBGene00013782 | View | |
Y53G8AM.4 | Y53G8AM.4 | WBGene00021804 | View | |
ZK1053.1 | ZK1053.1 | WBGene00014196 | View | |
ZK1320.5 | ZK1320.5 | WBGene00014255 | View |