Module
- Number
- 161
- Regulatory Genes
- 4
- Module Genes
- 6
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
srg-15 | C34C6.1 | WBGene00005172 | 304 | View | |
ras-2 | F17C8.4 | WBGene00004311 | 152 |
ras-2 encodes member of the Ras subfamily of RAS small GTPases with highest similarity to human M-Ras
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sur-6 | F26E4.1 | WBGene00006352 | 145 |
sur-6 encodes a regulatory (B) subunit of serine/threonine protein phosphatase 2A (PP2A-B); sur-6 was initially identified in screens for mutations that suppress the Multivulva phenotype produced by an activated let-60/Ras mutation and enhance the vulvaless and larval lethality phenotype of a hypomorphic lin-45/Raf mutation; in addition, RNAi experiments demonstrate that sur-6 activity is also essential for embryonic development; genetic studies indicate that during vulval development SUR-6 likely acts with the KSR-1 kinase in a parallel pathway that positively regulates RTK-Ras-MAP kinase signaling.
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Y65B4BR.5 | Y65B4BR.5 | WBGene00022042 | 135 | View |
CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
rpl-17 | Y48G8AL.8 | WBGene00004429 |
rpl-17 encodes a large ribosomal subunit L17 protein; by homology, RPL-17 is predicted to function in protein biosynthesis; in C. elegans, RPL-17 activity is required for embryonic and germline development, as well as normal postembryonic growth rates.
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rpl-23 | B0336.10 | WBGene00004435 |
rpl-23 encodes a large ribosomal subunit L23 protein.
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rpl-33 | F10E7.7 | WBGene00004447 |
rpl-33 encodes a large ribosomal subunit L35a protein.
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rps-1 | F56F3.5 | WBGene00004470 |
rps-1 encodes a small ribosomal subunit S3A protein.
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rps-24 | T07A9.11 | WBGene00004493 |
rps-24 encodes a small ribosomal subunit S24 protein; by homology, RPS-24 is predicted to function in protein biosynthesis; in C. elegans, RPS-24 activity is required for germline development and the overall health of the animal.
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rps-25 | K02B2.5 | WBGene00004494 |
rps-25 encodes a small ribosomal subunit S25 protein.
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