Module
- Number
- 112
- Regulatory Genes
- 3
- Module Genes
- 24
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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tlp-1 | T23G4.1 | WBGene00006580 | 674 |
The tlp-1 gene encodes a C2H2-type zinc finger of the Sp-1-like protein family, which is required for normal asymmetry in the divisions of the T.p and T.ap cells; such asymmetry, in turn, is required for normal, rounded tail morphology in adult males.
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pac-1 | C04D8.1 | WBGene00015418 | 339 |
pac-1 encodes a RhoGAP (Rho guanosine triphosphatase (GTPase) activating protein); in the embryo, PAC-1 is essential for establishment of radial (inner-outer) asymmetry and specifically, for differential localization of PAR-6, PAR-3, and PKC-3 to outer somatic cell surfaces devoid of cell-cell contacts; in regulating PAR protein localization, PAC-1 appears to act by spatially regulating activity of the CDC-42 Rho GTPase which can bind PAR-6 and is required, genetically, for PAR-6 localization to the outer cell surface; a PAC-1::GFP fusion protein expressed in the early embryo and in cultured embryos localizes to points of cell-cell contact.
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ctbp-1 | F49E10.5 | WBGene00006424 | 177 |
tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
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CLR Predictions
16 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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B0513.4 | B0513.4 | WBGene00007196 | View | |
C04H5.7 | C04H5.7 | WBGene00007315 | View | |
C10G8.4 | C10G8.4 | WBGene00015683 |
C10G8.4 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C10G8.4 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C10G8.4 has no obvious function in mass RNAi assays.
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C17G1.2 | C17G1.2 | WBGene00007649 | View | |
C25A8.4 | C25A8.4 | WBGene00016084 | View | |
C35B1.4 | C35B1.4 | WBGene00016434 | View | |
C44B7.5 | C44B7.5 | WBGene00016627 | View | |
C45B2.1 | C45B2.1 | WBGene00016658 | View | |
col-20 | F11G11.11 | WBGene00000609 |
col-20 encodes a collagen; its expression pattern and mutant phenotypes are unknown.
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F48E3.4 | F48E3.4 | WBGene00018605 | View | |
F49E12.1 | F49E12.1 | WBGene00009897 | View | |
F54F7.3 | F54F7.3 | WBGene00010065 | View | |
F55B11.2 | F55B11.2 | WBGene00010084 | View | |
F57C2.4 | F57C2.4 | WBGene00010196 | View | |
inx-8 | ZK792.2 | WBGene00002130 |
inx-8 encodes a predicted member of the innexin family that affects fertility; expressed in sheath cells.
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K07A1.6 | K07A1.6 | WBGene00010613 |
K07A1.6 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K07A1.6 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; K07A1.6 has no obvious function in mass RNAi assays.
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nas-20 | T11F9.3 | WBGene00003539 |
nas-20 encodes an astacin-like metalloprotease.
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T01H3.4 | T01H3.4 | WBGene00011350 |
T01H3.4 encodes an unfamiliar protein; T01H3.4 and T01H3.5 share an operon divergently transcribed from another operon containing vha-4.
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Y45F10C.4 | Y45F10C.4 | WBGene00012880 | View | |
Y57G11B.5 | Y57G11B.5 | WBGene00013297 | View | |
Y62H9A.6 | Y62H9A.6 | WBGene00013394 | View | |
Y75B12B.1 | Y75B12B.1 | WBGene00013567 |
Y75B12B.1 encodes a probable transposase, with many C. elegans paralogs and distant similarity to rotifer and insect transposases; Y75B12B.1 has no known function in mass RNAi assays; Y75B12B.1 mRNA is stabilized by bound GLD-1.
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ZK105.1 | ZK105.1 | WBGene00022653 | View | |
ZK813.2 | ZK813.2 | WBGene00022821 | View |