Module
- Number
- 111
- Regulatory Genes
- 4
- Module Genes
- 15
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
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2L52.1 | 2L52.1 | WBGene00007063 | 877 |
2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
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ppfr-4 | Y71H2B.3 | WBGene00022193 | 479 |
ppfr-4 encodes the C. elegans ortholog of TAP42, a protein phosphatase 2A (PP2A) regulatory subunit; ppfr-4(RNAi) in wild-type animals results in fertility defects in F1 hermaphrodites, who exhibit a 90-95% decrease in the total number of eggs laid.
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lin-15B | ZK662.4 | WBGene00023497 | 157 |
lin-15B encodes a novel protein that contains a THAP domain, a zinc-coordinating, site-specific DNA-binding domain; lin-15B was first identified as a class B synMuv gene that acts redundantly with lin-15A to negatively regulate the outcome of Ras signaling during vulval cell fate specification; subsequently, lin-15B has been shown to also negatively regulate progression through the G1 phase of the cell cycle and RNA-mediated interference (RNAi).
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ZC204.2 | ZC204.2 | WBGene00022554 | 103 | View |
CLR Predictions
4 are found.Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
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C18D11.3 | C18D11.3 | WBGene00007681 | View | |
K04G11.4 | K04G11.4 | WBGene00010572 | View | |
R01H10.7 | R01H10.7 | WBGene00010975 | View | |
stip-1 | C07E3.1 | WBGene00007412 | View | |
T24B8.7 | T24B8.7 | WBGene00011980 | View | |
teg-1 | Y47D3A.27 | WBGene00006563 | View | |
xrn-1 | Y39G8C.1 | WBGene00012730 |
xrn-1 encodes a 5'-3' exoribonuclease that is orthologous to Saccharomyces cerevisiae Xrnp1, a key component of the yeast 5'-3' mRNA degradation pathway; in C. elegans, XRN-1 activity is required during embryogenesis for completion of ventral enclosure, the morphogenetic process whereby the ventral epithelial cells cover and seal the interior cells of the embryo; in addition, XRN-1 also plays a role in facilitating RNA interference (RNAi), likely acting in the same pathway as the DCR-1/Dicer ribonuclease; to date, XRN-1 expression has been reported in adult hypodermal and rectal cells.
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Y105E8A.14 | Y105E8A.14 | WBGene00013674 | View | |
Y105E8A.29 | Y105E8A.29 | WBGene00013686 | View | |
Y111B2A.25 | Y111B2A.25 | WBGene00014613 | View | |
Y39G10AR.18 | Y39G10AR.18 | WBGene00021474 | View | |
Y50D7A.4 | Y50D7A.4 | WBGene00021754 | View | |
Y55F3BL.2 | Y55F3BL.2 | WBGene00021936 | View | |
Y57A10A.28 | Y57A10A.28 | WBGene00013268 | View | |
Y71H2AM.17 | Y71H2AM.17 | WBGene00022182 | View |