Module
- Number
- 110
- Regulatory Genes
- 3
- Module Genes
- 15
Regulatory Genes
Public Gene Name | Sequence Name | WB ID | Weight | Description | Actions |
---|---|---|---|---|---|
srg-3 | C18F10.6 | WBGene00005161 | 632 | View | |
srg-14 | F26B1.6 | WBGene00005171 | 171 | View | |
srg-45 | C51F7.2 | WBGene00005202 | 107 | View |
CLR Predictions
None
Module Genes
Public Gene Name | Sequence Name | WB ID | Description | Actions |
---|---|---|---|---|
btb-1 | F40G9.4 | WBGene00001963 | View | |
col-40 | T13B5.4 | WBGene00000617 |
col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.
|
View |
daf-2 | Y55D5A.5 | WBGene00000898 |
daf-2 encodes a predicted receptor tyrosine kinase that is the C. elegans insulin/IGF receptor ortholog; DAF-2 activity is required for a number of processes in C. elegans, including embryonic and larval development, formation of the developmentally arrested dauer larval stage, adult longevity, reproduction, fat storage, salt chemotaxis learning, and response to exogenous stressors such as high temperature or bacterial infection; DAF-2 signals through a conserved PI 3-kinase pathway to negatively regulate the activity of DAF-16, a Forkhead-related transcription factor, by inducing its phosphorylation and nuclear exclusion; in addition, DAF-2 negatively regulates the nuclear localization, and hence transcriptional activity, of SKN-1 in intestinal nuclei; amongst the 38 predicted insulin-like molecules in C. elegans, genetic and microarray analyses suggest that at least DAF-28, INS-1, and INS-7 are likely DAF-2 ligands; genetic mosaic and tissue-specific promoter studies indicate that daf-2 can function cell nonautonomously and within multiple cell types to influence dauer formation and adult lifespan, likely by regulating the production of secondary endocrine signals that coordinate growth and longevity throughout the animal.
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View |
F53F4.1 | F53F4.1 | WBGene00009985 | View | |
F55E10.1 | F55E10.1 | WBGene00018881 | View | |
F56C3.7 | F56C3.7 | WBGene00018944 | View | |
fbxa-97 | C18B12.5 | WBGene00007667 | View | |
K05C4.8 | K05C4.8 | WBGene00010584 | View | |
nhr-82 | F41D3.1 | WBGene00003672 | View | |
srh-33 | M02H5.9 | WBGene00005256 | View | |
srw-7 | R08F11.5 | WBGene00005754 | View | |
tag-348 | T04H1.1 | WBGene00011448 | View | |
ver-1 | T17A3.1 | WBGene00006894 | View | |
W02H5.5 | W02H5.5 | WBGene00020960 | View | |
ZK697.8 | ZK697.8 | WBGene00022808 | View |