Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

pie-1  

Sequence Name

Y49E10.14  

WB ID

WBGene00004027  

Description

pie-1 encodes a C-x8-C-x5-C-x3-H-type zinc-finger protein; maternally provided PIE-1 is essential for germline cell fate determination, as it functions as a repressor of RNA polymerase II-dependent gene expression in the developing germ line; PIE-1 localization, initially uniform and then concentrated in the posterior germ cell lineages, is regulated by other maternally supplied gene products including PAR-1, MEX-5, and MEX-6.