Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

pab-1  

Sequence Name

Y106G6H.2  

WB ID

WBGene00003902  

Description

pab-1 encodes a polyadenylate-binding protein (i.e., poly(A)-binding protein, or PAB); pab-1 is essential for germline proliferation, regulation of adult lifespan, and normal body size; PAB-1 forms a complex with ATX-2, the C. elegans ataxin 2 ortholog, which is also required for germline development; PAB-1 has been successfully used as an epitope-tagged transgenic reagent for tissue-specific isolation of mRNAs.