Gene
- Public Gene Name
- mca-1
- Sequence Name
- W09C2.3
- WB ID
- WBGene00003151
- Description
- mca-1 encodes one of three C. elegans plasma membrane Ca2+ ATPases (PMCAs); by homology, MCA-1 is predicted to function as a molecular pump that couples ATP hydrolysis to extrusion of cytosolic Ca2+; when expressed in insect cells, MCA-1 exhibits calcium-pumping ATPase activity and binding to human calmodulin; large-scale RNAi screens indicate that mca-1 activity is required for normal coordinated locomotion and rates of growth; an mca-1::gfp reporter fusion is expressed solely in the excretory canal.
