Gene
- Public Gene Name
- hst-1
- Sequence Name
- F08B4.6
- WB ID
- WBGene00002028
- Description
- hst-1 encodes the C. elegans ortholog of N-deacetylase/N-sulfotransferase (NDST), a bifunctional enzyme that catalyzes N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate; loss of hst-1 activity has been reported to result in embryonic lethality at various stages of development, defects in ventral neuroblast migrations during epidermal enclosure, and cessation of egg production in injected hermaphrodites.
