Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name

exp-1  

Sequence Name

H35N03.1  

WB ID

WBGene00001373  

Description

exp-1 encodes an excitatory, cation-selective GABA receptor; EXP-1 activity is essential for the enteric muscle contractions that are the third in a series of three independent muscle contractions controlling defecation, and when expressed in Xenopus oocytes, EXP-1 is capable of forming a cation-selective GABA receptor; a rescuing EXP-1::GFP reporter fusion is expressed in the intestinal and anal depressor muscles, where it localizes to regions consistent with the positions of neuromuscular junctions; expression is also observed in neurons, including PDA, RID, ADE, and SABD.