Gene
- Public Gene Name
- clp-6
- Sequence Name
- Y77E11A.10
- WB ID
- WBGene00000546
- Description
- clp-6 encodes a calpain homolog that has significant identity to mammalian calpains over its whole length and that contains motifs typical of calpains, including a thiol (cysteine) protease active site and a Ca[2+]-binding domain; CLP-6 is not required for degenerative (necrotic-like) cell death in neurons induced by mutations such as mec-4(d), deg-3(d), or gsa-1(gf), since clp-6(RNAi) has no effect on such degeneration.
