Transcription regulatory networks in Caenorhabditis elegans

Gene

Public Gene Name
ced-10  
Sequence Name
C09G12.8  
WB ID
WBGene00000424  
Description
ced-10 encodes a GTPase orthologous to human RAC1 (OMIM:602048) that is required for phagocytosis during programmed cell death and for migration of the distal tip cells of the somatic gonad; CED-10 functions in the engulfing cell during apoptosis, and is activated by a complex of CED-2(CrkII) and CED-5(DOCK180) to promote formation of the polarized cell extensions associated with cell corpse engulfment.  


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