Gene
- Public Gene Name
- aman-3
- Sequence Name
- F48C1.1
- WB ID
- WBGene00018594
- Description
- aman-3 encodes a Co(II)-activated alpha-mannosidase II, orthologous to human MAN2C1; AMAN-3 is predicted to remove mannose residues from the N-linked oligosaccharides of glycoproteins; AMAN-3 contains three predicted N-glycosylation sites; AMAN-3 is biochemically active in vitro, with a pH optimum of 6.5; AMAN-3 requires either Co(II) or Mn(II) for activity, preferring the former ion; since aman-2(tm1078) mutants almost completely lack paucimannosidic glycans, the function of AMAN-3 in vivo is unclear.
