Predicting protein-protein interactions in
Arabidopsis thaliana through integration of orthology, gene ontology and
Stefanie De Bodt, Sebastian Proost, Klaas Vandepoele, Pierre Rouzé, Yves Van
Please also check out:
1. Query Arabidopsis protein-protein
2. Download Supplementary data
Figure S1. Calculation of GO similarity score. All possible GO terms of two proteins are compared in a pairwise manner. For each pair of GO terms (in green), the depth of the common ancestor (in blue) of these terms is calculated. The maximum depth of all pairwise combinations of GO terms is considered as the GO similarity score between two proteins.
Figure S2. Assessment of combinations of genomic features.
Figure S3. Overlap of the filtered (1) and predicted (2) interactome with previously experimentally shown (A) and predicted protein-protein interactions (B).
Table S1. False positive rates for different combinations of genomic features (BP=biological process, CC=cellular component, PCC=Pearson Correlation Coefficient)
Protein-protein interactions that passed the genomic feature filters. BP score >= 8, CC score >= 5 or BP score>=5 + PCC >=0.3)
Extension of filtered interactome. Interactions with orthologous group combination already present in filtered interactome are included
3. View Arabidopsis protein-protein interactions discussed in our manuscript
CELL CYCLE + DNA
REPAIR + DNA REPLICATION