This entry represents the several classes of P-type ATPases, including those that transport K⁺ (3.6.3.12), Mg²⁺ (3.6.3.2), Cd²⁺ (3.6.3.3), Cu ²⁺ (3.6.3.4), Zn²⁺ (3.6.3.5), Na⁺ (3.6.3.7), Ca²⁺ (3.6.3.8), Na⁺/K⁺ (3.6.3.9), and H⁺/K⁺ (3.6.3.10). These P-ATPases are found in both prokaryotes and eukaryotes [1]. They are cation transport ATPases which form an aspartyl phosphate intermediate in the course of ATP hydrolysis. The region around the phosphorylated aspartate residue is perfectly conserved in all these ATPases and it is represented by this entry.

1. P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees. J. Mol. Evol. 38, 57-99

This entry represents the several classes of P-type ATPases, including those that transport KShow more...

Download genes (select columns to include)