This family represents a group of glycosyltransferases from plants and fungi, including Mnn10/Mnn11 from budding yeasts, Gma12/Gmh1-3 from fission yeasts and xyloglucan 6-xylosyltransferase 1/2 (XXT1/XXT2) from Arabidopsis.

Mnn10 and Mnn11 are subunits of a Golgi mannosyltransferase complex, which mediates elongation of the polysaccharide mannan backbone [1].

Gma12 is involved in the O- and N-linked oligosaccharide modification of proteins transported through the Golgi stack, while Gmh3 is involved in the galactosylation of the N-linked core oligosaccharide Man9GlcNAc2 [2].

XXT1 and XXT2 are xylosyltransferases specific to UDP-D-xylose that accepts both cellopentaose and cellohexaose as substrates, with a better use of cellohexaose, to produce xyloglucan [3].

1. The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex. J. Biol. Chem. 274, 6579-85
2. Differences in in vivo acceptor specificity of two galactosyltransferases, the gmh3+ and gma12+ gene products from Schizosaccharomyces pombe. Eur. J. Biochem. 257, 630-7
3. Disrupting two Arabidopsis thaliana xylosyltransferase genes results in plants deficient in xyloglucan, a major primary cell wall component. Plant Cell 20, 1519-37

This family represents a group of glycosyltransferases from plants and fungi, including Mnn10/Mnn
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