PLAZA 4.0 Monocots gene overview : AT5G50950

Gene: AT5G50950 (Arabidopsis thaliana)

Overview

Gene Identifier: AT5G50950
Transcript Identifier: AT5G50950.2
Gene Type: Coding gene
Location: Chr5 : 20729687-20733636 : positive

Family

Gene family: HOM04M003689
(47 genes in 29 species)
specific family

Descriptions

Description: FUMARASE 2

Curated Summary: Encodes a fumarase enzyme initially shown to be in the mitochondria through proteomic studies but later shown to be present in the cytosol using an RFP fluorescent protein tag. It appears to be important for the accumulation of fumarate from malate in leaves in the light, and helps to promote nitrogen assimilation under high nitrogen conditions. It does not appear to be necessary for lipid metabolism and seedling growth.

Identifiers

Type	Value
symbol	FUM2
tid	AT5G50950.2
UniProt	Q9FI53

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Biological Process

GO term	Evidence(s)	Provider	Description	Source
GO:0006106	IEA, IMP,	UniProt	fumarate metabolic process	1 2
GO:0006099	IBA, IEA,	UniProt	tricarboxylic acid cycle	1 2
GO:0006108	IBA	UniProt	malate metabolic process	1
GO:0009651	IEP	UniProt	response to salt stress	1
GO:0042128	IMP	UniProt	nitrate assimilation	1
GO:0009631	IMP	UniProt	cold acclimation	1 2
GO:0010109	IMP	UniProt	regulation of photosynthesis	1 2
GO:0048868	IEA	PLAZA Integrative Orthology	pollen tube development	AT2G47510
GO:0006979	IEA	PLAZA Integrative Orthology	response to oxidative stress	AT2G47510

Molecular Function

GO term	Evidence(s)	Provider	Description	Source
GO:0004333	IEA, IMPISS,	UniProt	fumarate hydratase activity	1 2 3
GO:0016829	IEA	InterPro	lyase activity
GO:0003824	IEA	InterPro	catalytic activity
GO:0005515	IPI	Gene Ontology	protein binding	1

Cellular Component

GO term	Evidence(s)	Provider	Description	Source
GO:0045239	IEA	UniProt	tricarboxylic acid cycle enzyme complex	1
GO:0005739	IDA, ISM,	UniProt	mitochondrion	1 2
GO:0009507	IEA	UniProt	chloroplast	1
GO:0005829	IDA	UniProt	cytosol	1

Color Legend

Experimental Evidence

Electronic Evidence

Computational Reviewed Evidence

InterPro	Description
IPR024083	Fumarase/histidase, N-terminal
IPR005677	Fumarate hydratase, class II
IPR022761	Fumarate lyase, N-terminal
IPR018951	Fumarase C, C-terminal
IPR000362	Fumarate lyase family
IPR020557	Fumarate lyase, conserved site
IPR008948	L-Aspartase-like

Mapman id	Description
2.3.7	.Cellular respiration.tricarboxylic acid cycle.fumarase

No SignalP domains detected for this gene.