Gene: AT5G50950 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G50950
Transcript Identifier
AT5G50950.2
Gene Type
Coding gene
Location
Chr5 : 20729687-20733636 : positive

Family

Gene family
HOM04M003689
(47 genes in 29 species)
specific family

Descriptions

Description
FUMARASE 2
Curated Summary
Encodes a fumarase enzyme initially shown to be in the mitochondria through proteomic studies but later shown to be present in the cytosol using an RFP fluorescent protein tag. It appears to be important for the accumulation of fumarate from malate in leaves in the light, and helps to promote nitrogen assimilation under high nitrogen conditions. It does not appear to be necessary for lipid metabolism and seedling growth.
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Identifiers

Type Value
symbolFUM2
tidAT5G50950.2
UniProtQ9FI53

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0006106 IEA, IMP, UniProtfumarate metabolic process1 2
GO:0006099 IBA, IEA, UniProttricarboxylic acid cycle1 2
GO:0006108 IBAUniProtmalate metabolic process1
GO:0009651 IEPUniProtresponse to salt stress1
GO:0042128 IMPUniProtnitrate assimilation1
GO:0009631 IMPUniProtcold acclimation1 2
GO:0010109 IMPUniProtregulation of photosynthesis1 2
GO:0048868 IEAPLAZA Integrative Orthologypollen tube developmentAT2G47510
GO:0006979 IEAPLAZA Integrative Orthologyresponse to oxidative stressAT2G47510

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004333 IEA, IMPISS, UniProtfumarate hydratase activity1 2 3
GO:0016829 IEAInterProlyase activity
GO:0003824 IEAInterProcatalytic activity
GO:0005515 IPIGene Ontologyprotein binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0045239 IEAUniProttricarboxylic acid cycle enzyme complex1
GO:0005739 IDA, ISM, UniProtmitochondrion1 2
GO:0009507 IEAUniProtchloroplast1
GO:0005829 IDAUniProtcytosol1

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR024083Fumarase/histidase, N-terminal
IPR005677Fumarate hydratase, class II
IPR022761Fumarate lyase, N-terminal
IPR018951Fumarase C, C-terminal
IPR000362Fumarate lyase family
IPR020557Fumarate lyase, conserved site
IPR008948L-Aspartase-like

Mapman id Description
2.3.7.Cellular respiration.tricarboxylic acid cycle.fumarase
No SignalP domains detected for this gene.