Gene: AT5G48820 (Arabidopsis thaliana)

Overview top

Gene Identifier
AT5G48820
Transcript Identifier
AT5G48820.1
Gene Type
Coding gene
Location
Chr5 : 19792608-19794346 : negative

Family

Gene family
HOM04M001414
(104 genes in 25 species)
specific family

Descriptions

Description
inhibitor/interactor with cyclin-dependent kinase
Curated Summary
Kip-related protein (KRP) gene, encodes CDK (cyclin-dependent kinase) inhibitor (CKI), negative regulator of cell division. Binds to D type and CDC2A cyclins and may inhibit cell cycle. Seven KRP genes were found in Arabidopsis thaliana. Differential expression patterns for distinct KRPs were revealed by in situ hybridization.
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Identifiers

Type Value
AliasKRP3,KIP-RELATED PROTEIN 3
symbolICK6
tidAT5G48820.1
UniProtQ9FKB5

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0007050 IEAUniProtcell cycle arrest1
GO:0016310 IEAGene Ontologyphosphorylation1
GO:0045736 IDA, TAS, UniProtnegative regulation of cyclin-dependent protein serine/threonine kinase activity1 AGRICOLA_IND:IND233052532
GO:0010311 IEAPLAZA Tree-based Orthologylateral root formationAT2G23430
GO:0032877 IEAPLAZA Integrative Orthologypositive regulation of DNA endoreduplicationAT3G24810
GO:0000082 IEAPLAZA Tree-based OrthologyG1/S transition of mitotic cell cycleAT2G23430
GO:0048366 IEAPLAZA Tree-based Orthologyleaf developmentAT2G23430
GO:0048367 IEAPLAZA Tree-based Orthologyshoot system developmentAT2G23430
GO:0009737 IEAPLAZA Tree-based Orthologyresponse to abscisic acidAT2G23430
GO:0048527 IEAPLAZA Tree-based Orthologylateral root developmentAT2G23430
GO:0045740 IEAPLAZA Tree-based Orthologypositive regulation of DNA replicationAT2G23430
GO:0042023 IEAPLAZA Tree-based OrthologyDNA endoreduplicationAT3G19150
GO:0045786 IEAPLAZA Tree-based Orthologynegative regulation of cell cycleAT2G32710

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0004861 IEA, IGI, TAS, UniProtcyclin-dependent protein serine/threonine kinase inhibitor activity1 2 AGRICOLA_IND:IND233052533
GO:0016301 IEAUniProtkinase activity1
GO:0030332 IPIGene Ontologycyclin binding1 AGRICOLA_IND:IND23305253
GO:0005515 IPIGene Ontologyprotein binding1
GO:0031490 IEAPLAZA Integrative Orthologychromatin DNA bindingAT3G24810

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005634 IDA, ISMIEA, UniProtnucleus1 2
GO:0005654 IEAUniProtnucleoplasm1
GO:0016021 IEAUniProtintegral component of membrane1
GO:0005737 IEAPLAZA Tree-based OrthologycytoplasmAT2G32710
GO:0001673 IEAPLAZA Tree-based Orthologymale germ cell nucleusAT1G49620

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Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR003175Cyclin-dependent kinase inhibitor

Mapman id Description
13.1.1.3.1.Cell cycle organisation.cell cycle control.cyclin-dependent regulation.cyclin-dependent protein kinase inhibitor activities.inhibitor (KRP/ICK)
No SignalP domains detected for this gene.