Gene: AT5G48230 (Arabidopsis thaliana)

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Gene Identifier
AT5G48230
Transcript Identifier
AT5G48230.2
Gene Type
Coding gene
Location
Chr5 : 19552570-19555122 : negative

Family

Gene family
HOM04M001945
(80 genes in 28 species)
specific family
Subfamily
ORTHO04M002422
(70 genes in 28 species)
specific family

Descriptions

Description
acetoacetyl-CoA thiolase 2
Curated Summary
Encodes an acetoacetyl-CoA thiolase that generates the bulk of the acetoacetyl-CoA precursor needed for the cytosolic localized, mevalonate-derived isoprenoids biosynthetic pathway. Loss-of-function mutants are embryo lethal.
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Identifiers

Type Value
AliasAACT2,Acetoacetyl-CoA thiolase 2,EMB1276,EMBRYO DEFECTIVE 1276
symbolACAT2
tidAT5G48230.2
UniProtQ8S4Y1

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Biological Process

GO termEvidence(s)ProviderDescriptionSource
GO:0008152 IEAInterPrometabolic process
GO:0006635 IBAGene Ontologyfatty acid beta-oxidation1
GO:0008299 IEAGene Ontologyisoprenoid biosynthetic process1
GO:0009793 NASGene Ontologyembryo development ending in seed dormancy1
GO:0009846 IMPGene Ontologypollen germination1
GO:0009860 IMPGene Ontologypollen tube growth1
GO:0016125 IMPGene Ontologysterol metabolic process1

Molecular Function

GO termEvidence(s)ProviderDescriptionSource
GO:0003824 IEAInterProcatalytic activity
GO:0016747 IEAInterProtransferase activity, transferring acyl groups other than amino-acyl groups
GO:0003985 IDA, IGI, ISSGene Ontologyacetyl-CoA C-acetyltransferase activity1 2 3
GO:0046872 IEAGene Ontologymetal ion binding1

Cellular Component

GO termEvidence(s)ProviderDescriptionSource
GO:0005737 ISMGene Ontologycytoplasm1
GO:0005886 IDAGene Ontologyplasma membrane1
GO:0005777 IDAGene Ontologyperoxisome1
GO:0005829 IDAGene Ontologycytosol1

Color Legend

Experimental Evidence
Electronic Evidence
Computational Reviewed Evidence
GO Sources:   Primary     Orthology     Homology  
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InterPro Description
IPR016039Thiolase-like
IPR020616Thiolase, N-terminal
IPR020617Thiolase, C-terminal
IPR002155Thiolase
IPR020613Thiolase, conserved site
IPR020615Thiolase, acyl-enzyme intermediate active site
IPR020610Thiolase, active site

Mapman id Description
9.1.1.1.Secondary metabolism.terpenoids.mevalonate pathway.acetyl-CoA C-acyltransferase
No SignalP domains detected for this gene.